4229-69-0

Basic information

• Product Name: 5-bromo-3,6-dihydroxyandrostan-17-one-3-acetate
• Synonyms: 5-bromo-3,6-dihydroxyandrostan-17-one-3-acetate;(3β, 5α, 6β)-3-(acetyloxy)-5-bromo-6-hydroxy-androstan-17-one
• CAS NO: 4229-69-0
• Molecular Formula: C21H31 Br O4
• Molecular Weight: 427.37
• EINECS: 419-790-7
• Mol File: 4229-69-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 497.3°Cat760mmHg
• Flash Point: 254.5°C
• Appearance: /
• Density: 1.36g/cm³
• CAS DataBase Reference: 5-bromo-3,6-dihydroxyandrostan-17-one-3-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-3,6-dihydroxyandrostan-17-one-3-acetate(4229-69-0)
• EPA Substance Registry System: 5-bromo-3,6-dihydroxyandrostan-17-one-3-acetate(4229-69-0)

Safety Data

• Hazard Codes: Xi
• Statements: 43-52/53
• Safety Statements: 22-36/37-61
• Hazardous Substances Data: 4229-69-0(Hazardous Substances Data)

Upstream product

• 853-23-6 prasterone acetate 

Downstream Products

• 6901-40-2 19,21-dihydroxypregn-4-ene-3,20-dione 21-acetate 
• 2394-23-2 19,21-dihydroxypregn-4-ene-3,20-dione 
• 4682-70-6 19-Nordeoxycorticosterone 
• 88378-35-2 19-oxo-11-deoxycorticosterone acetate 
• 75220-37-0 19-oxo-deoxycorticosterone 
• 2857-42-3 3β-acetoxy-19-hydroxyandrost-5-en-17-one 
• 18386-45-3 3β-Hydroxyandrost-4-ene-6,17-dione 
• 2685-64-5 5-bromo-6β,19-oxido-3β-hydroxy-5α-androstan-17-one 3-acetate 
• 6585-68-8 3β-acetoxy-5β,6β-epoxyandrostan-17-one 

Relevant articles and documents

Synthetic study of strongylophorines: stereoselective construction of the characteristic lactone bridge

Herein, we report an efficient construction of the lactone bridge of strongylophorine-2, which is a meroditerpenoid isolated from Strongylophora durissima and an inhibitor for HIF-1 transcriptional pathway. Starting from dehydroepiandrosterone acetate, the characteristic lactone has been constructed in 5.4% over 18 steps by employing, (1) modified oxy radical-mediated C–H functionalization at the C24 methyl group, and (2) four-step manipulation of C4 quaternary carbon stereogenic center. The lactone synthesized here is expected as a precursor for (8-desmethyl)strongylophorine-2 which is of particular interest in terms of structure–activity relationships in the inhibition of HIF-1 transcriptional pathway.

Convenient preparative routes to 19-hydroxy, 19-oxo-, 19-oic-, and 19-nor-deoxycorticosterone

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The synthesis of 3-beta, 16-alpha, 19-trihydroxyandrost-5-en-17-one.

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