42330-59-6Relevant articles and documents
Formation of Aryl [1-Cyano-4-(dialkylamino)butadienyl] Ketones from Pyridines
Gim, Hyo Jin,Jung, Michael E.
supporting information, p. 2548 - 2552 (2019/06/08)
Treatment of 2-chloropyridine with LDA and the Weinreb amide of benzoic acid afforded three unusual products, namely N -methylbenzamide, 2-chloropyridine-3-methanol, and the ring-opened addition product. This same final product could also be obtained from 2-chloro-3-benzoylpyridine on treatment with LDA. Mechanistic insight for the formation of these products is provided.