42716-73-4 Usage
Uses
Used in Pharmaceutical Industry:
BROMO-CYCLOHEXYL-ACETIC ACID ETHYL ESTER is used as a chemical intermediate for the synthesis of various drugs. Its unique structure, including the bromine atom and ester group, allows it to be a key component in the development of pharmaceutical compounds with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, BROMO-CYCLOHEXYL-ACETIC ACID ETHYL ESTER is utilized as a precursor in the production of pesticides. Its chemical properties make it suitable for the creation of active ingredients that can effectively control, repel, or kill pests, thereby contributing to crop protection and increased agricultural yields.
Used in Specialty Chemicals Manufacturing:
BROMO-CYCLOHEXYL-ACETIC ACID ETHYL ESTER also serves as a chemical building block in the manufacture of specialty chemicals. Its versatility and reactivity enable its use in the development of a wide range of specialty chemicals for various applications, including but not limited to coatings, adhesives, and fragrances.
Check Digit Verification of cas no
The CAS Registry Mumber 42716-73-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,7,1 and 6 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 42716-73:
(7*4)+(6*2)+(5*7)+(4*1)+(3*6)+(2*7)+(1*3)=114
114 % 10 = 4
So 42716-73-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H17BrO2/c1-2-13-10(12)9(11)8-6-4-3-5-7-8/h8-9H,2-7H2,1H3
42716-73-4Relevant academic research and scientific papers
Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties
Richter, Hans G.F.,Benson,Bleicher,Blum,Chaput,Clemann,Feng,Gardes,Grether,Hartman,Kuhn,Martin,Plancher,Rudolph,Schuler,Taylor
, p. 1134 - 1140 (2011/04/16)
Structure-guided lead optimization of recently described benzimidazolyl acetamides addressed the key liabilities of the previous lead compound 1. These efforts culminated in the discovery of 4-{(S)-2-[2-(4-chloro-phenyl)-5,6- difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetylamino}-3-fluoro-benzoic acid 7g, a highly potent and selective FXR agonist with excellent physicochemical and ADME properties and potent lipid lowering activity after oral administration to LDL receptor deficient mice.
Intermolecular C-H and Si-H insertion reactions with halodiazoacetates
Bonge, Hanne Therese,Hansen, Tore
experimental part, p. 91 - 96 (2009/06/24)
Ethyl halodiazoacetates react with a range of substrates in regioselective rhodium(II)-catalysed C-H and Si-H insertion reactions giving α-halocarbonyl products in up to 82% yield. The halodiazoacetates are a novel class of diazo compounds that can undergo intermolecular carbenoid C-H insertion reactions, thus broadening the synthetic utility of such reactions. Georg Thieme Verlag Stuttgart.
