42746-80-5Relevant academic research and scientific papers
One-pot synthesis of α,α-disubstituted Aryl-1-ethanones via the Wittig-Horner reaction
Yang, Yunxia,Wang, Le,Chen, Yuan,Dai, Yiru,Sun, Zhihua
, p. 121 - 126 (2018/01/04)
A one-pot methodology for the synthesis of α,α-disubstituted aryl-1-ethanones via the Wittig-Horner reaction has been developed and described in this manuscript. Both aryl/alkyl and dialkyl α-branched arylethanone were obtained in high yields (up to 96%) without the use of any metal catalysts. A total of 14 α,α-disubstituted arylethanone derivatives were synthesized based on this simple method that easily converts the carbonyl carbon (sp2) into the sp3 carbon. This versatile method is expected to further promote the use of substituted ketones as synthetic building blocks to construct a variety of α-branched aryl ketones.
Palladium-catalyzed C-C bond formation: Synthesis of 1,1-dialkylbuta-1,3-dienes and β-phenylstyrenes via organoboron intermediates
Deagostino, Annamaria,Prandi, Cristina,Zavattaro, Chiara,Venturello, Paolo
, p. 2612 - 2616 (2007/10/03)
α,β-Unsaturated and α-phenyl acetals show different reactivity when treated with LIC-KOR superbase and trialkylboranes, in the presence of the reagent system PdL4-ArX (Suzuki-Miyaura cross-coupling conditions). In particular, unsaturated acetal
Photolysis of Vinyl Halides. Preferential Formation of Vinyl Cations by Copper(II) Salts
Kitamura, Tsugio,Kobayashi, Shinjiro,Taniguchi, Hiroshi
, p. 2641 - 2645 (2007/10/02)
Photolysis of vinyl halides in the presence of copper(II) salts in a significant suppression of product formation derived from vinyl radicals.Photolysis of 1,1-diaryl-2-bromopropenes in the presence of copper(II) salts yielded no 1,1-diaryl-2-propenes.Photolysis of other vinyl halides, i.e., 1,1-diaryl-2-iodopropenes, 1,1-diaryl-2-bromoethylenes, and 1-bromo-2-(p-methoxyphenyl)ethylene, also led to a large decrease in the yields of the reduced olefins derived from the vinyl radicals.Copper(II) triflate was found to be more effective for the oxidation of vinyl radicals than copper(II) acetate.These reactions are explained by the intervention of vinylcopper intermediates and the formation of vinyl cations.
Peterson Olefination of (α-Methoxybenzyl)silane with Aldehydes and Ketones Leading to Vinyl Ethers
Kanemasa, Shui,Tanaka, Junji,Nagahama, Hideki,Tsuge, Otohiko
, p. 3385 - 3386 (2007/10/02)
(α-Methoxybenzyl)trimethylsilane is deprotonated with butyllithium and then allowed to react with a variety of carbonyl compounds giving vinyl ethers which are convertible into methyl ketones under mild conditions.
Photochemistry of Vinyl Halides. Vinyl Cation from Photolysis of 1,1-Diaryl-2-halopropenes
Kitamura, Tsugio,Kobayashi, Shinjiro,Taniguchi, Hiroshi
, p. 2323 - 2328 (2007/10/02)
Irradiation of 1,1-diaryl-2-halopropenes in methanol gave 1,1-diarylpropenes, 1,1-diarylallenes, 1,2-diaryl-1-methoxypropenes, and 9-methoxy-10-methylphenanthrenes.The propenes are derived from vinyl radicals which are generated by homolytic fission of th
