4280-58-4

Usage

Synonym

6-(4-Methoxybenzyl)hexylveratrol
Another name for the same chemical compound.

Family

Benzene derivatives
A group of chemical compounds related to benzene, a basic organic structure.

Origin

Synthetic derivative of resveratrol
A man-made version of a natural phenol found in red wine and various plants.

Therapeutic properties

Antioxidant and anti-inflammatory effects
The ability to neutralize harmful free radicals and reduce inflammation in the body.

Skincare applications

Protection against UV radiation and prevention of skin aging
The compound's potential to protect the skin from damage caused by ultraviolet light and slow down the aging process.

Combating diseases

Cancer and cardiovascular conditions
Research has shown the potential of 1-Methoxy-4-[6-(4-methoxyphenyl)hexyl]benzene in preventing and treating certain diseases, such as cancer and heart-related conditions.

Promise for various applications

Pharmacological properties and potential health benefits
The compound's potential for use in different fields, such as medicine and skincare, due to its beneficial properties and health advantages.

Upstream product

• 75-44-5 phosgene 
• 60-29-7 diethyl ether 
• 855907-73-2 1,6-dibromo-1,6-bis-(4-methoxy-phenyl)-hexane 
• 71-43-2 benzene 
• 629-03-8 1 ,6-dibromohexane 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 110146-59-3 1,6-bis-(4-methoxy-phenyl)-hex-1-ene 
• 64-19-7 acetic acid 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 832-01-9 methyl p-methoxycinnamate 
• 5406-18-8 3-(p-methoxyphenyl)-1-propanol 
• 15823-04-8 methyl 3-(4-methoxyphenyl)propionate 
• 140-67-0 Estragole 
• 111-50-2 Adipic acid dichloride 

Downstream Products

• 29668-19-7 1,6-Bis-(3-acetyl-4-hydroxyphenyl)-hexan 
• 136577-68-9 1,6-bis<3-(1-hydroxyethyl)-4-methoxyphenyl>hexane 
• 136559-26-7 1,6-bis(3-vinyl-4-methoxyphenyl)hexane 
• 204572-34-9 Acetic acid (2R,3R,4S,5S,6R)-3,5-diacetoxy-2-acetoxymethyl-6-(3'-hydroxy-5-{6-[3'-hydroxy-6-((2R,3S,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-biphenyl-3-yl]-hexyl}-biphenyl-2-yloxy)-tetrahydro-pyran-4-yl ester 
• 204572-18-9 Acetic acid (2R,3S,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-(2-bromo-4-{6-[3-bromo-4-((2R,3S,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-phenyl]-hexyl}-phenoxy)-tetrahydro-pyran-3-yl ester 
• 204572-33-8 1,6-bis(3-bromo-4-hydroxyphenyl)hexane 
• 204572-35-0 C₆₆H₇₈O₂₆ 
• 204572-32-7 1,6-bis(3-bromo-4-methoxyphenyl)hexane 
• 136559-21-2 1,6-bis(3-acetyl-4-methoxyphenyl)hexane 
• 127660-79-1 1,6-bis-(3-iodo-4-methoxyphenyl)hexane 
• 3682-95-9 1,6-bis(4-hydroxyphenyl)hexane 

Relevant academic research and scientific papers

Synthesis and Structures of [2.n]Metacyclophan-1-enes and their Conversion to Highly Strained [2.n]Metacyclophane-1-ynes

The syntheses of syn-[2.n]metacyclophan-1-enes (n = 5, 6, 8) in good yields using the McMurry cyclization of 1,n-bis(3-formyl-4-methoxyphenyl)alkanes are reported. Conversion of syn-[2.6]- and [2.8]metacyclophan-1-enes to the corresponding highly strained syn-type [2.6]- and [2.8]metacyclophane-1-ynes was achieved by successive bromination and dehydrobromination reactions. An attempted trapping reaction of the putative corresponding [2.5]metacyclophane-1-yne by Diels–Alder reaction with 1,3-diphenylisobenzofuran failed due to its smaller ring size and strained structure. X-ray crystallographic analyses show that the triple bonds in syn-[2.6]- and [2.8]metacyclophane-1-ynes are distorted from linearity with bond angles of 156.7° and 161.4°, respectively. A DFT (Density Functional Theory) computational study was conducted to determine the stabilities of different conformations of the target compounds.

Novel synthetic inhibitors of selectin-mediated cell adhesion: Synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-α-D-mannopyranosyloxy)phenyl] hexane (TBC1269)

Reports of a high-affinity ligand for E-selectin, sialyl di-Lewis(x) (sLe(x)Le(x), 1), motivated us to incorporate modifications to previously reported biphenyl-based inhibitors that would provide additional interactions with the protein. These compounds were assayed for the ability to inhibit the binding of sialyl Lewis(x) (sLe(x), 2) bearing HL-60 cells to E-, P-, and L- selectin fusion proteins. We report that dimeric or trimeric compounds containing multiple components of simple nonoligosaccharide selectin antagonists inhibit sLe(x)-dependent binding with significantly enhanced potency over the monomeric compound. The enhanced potency is consistent with additional binding interactions within a single selectin lectin domain; however, multivalent interaction with multiple lectin domains as a possible alternative cannot be ruled out. Compound 15e (TBC1269) showed optimal in vitro activity from this class of antagonists and is currently under development for use in the treatment of asthma.

Bisbenzoxazines and pharmaceutical use

Compounds of the formula: STR1 wherein, R is H, alkyl, cycloalkyl, aryl, or heteroaryl; R1 is H, alkyl, cycloalkyl, aryl, heteroaryl, substituted heteroaryl, aralkyl, substituted aryl, halo, OR2, SR2, NR2, CF3, NO2, CN, COOR2, CHO, SO3 H or SO2 NH2, wherein R2 is H, methyl, ethyl or propyl; Y is STR2 Z is O, S, NH or CH2 ; X is --CH2 --, STR3 or --(CH2)n CHOH(CH2)n --; wherein R2 is H, methyl, ethyl or propyl; n is 1-10, and pharmaceutically acceptable salts thereof have antiallergy and antiinflammatory activity.

THE PREPARATION OF α,ω-BIS-PARA-ANISYLALKANES

An improved method for the preparation of a homologous series of α,ω-bis-para-anisylalkanes is described.