42967-97-5

Upstream product

• 100-52-7 benzaldehyde 
• 78-94-4 methyl vinyl ketone 
• 73255-39-7 3-(hydroxyphenylmethyl)but-3-en-2-one 

Downstream Products

• 42968-01-4 3-(morpholin-4-yl-phenyl-methyl)-but-3-en-2-one 
• 42968-06-9 3-morpholin-4-ylmethyl-4-phenyl-but-3-en-2-one 
• 1190601-45-6 C₁₇H₁₇NO₃ 
• 1266358-99-9 C₂₈H₂₇NO₄ 
• 1310487-41-2 (Z)-S-2-benzylidene-3-oxobutyl benzothioate 
• 1516887-54-9 (3E,4E)-3-benzylidene-5-phenylpent-4-en-2-one 
• 2550-27-8 (2R)-3-methyl-4-phenylbutan-2-one 
• 14367-67-0 2-methyl-3-phenylpropionic acid 
• 2550-27-8 (3S)-3-methyl-4-phenylbutan-2-one 
• 29393-16-6 methyl (2R)-2-methyl-3-phenylpropanoate 
• 1078631-98-7 C₁₈H₂₀O₄ 
• 74693-17-7 2-Methyl-4-methylene-5-oxo-3-phenyl-hexanedithioic acid methyl ester 

Relevant academic research and scientific papers

Enantiodivergence in the reduction of α-methyl and α-halomethyl enones by microorganisms

Enones (Z)-3-methyl-(Z)-3-chloromethyl- and (Z)-3-bromomethyl-4-R-3-buten- 2-one (R = n-pentyl, phenyl, 2′- and 4′-chlorophenyl, 3′- and 4′-nitrophenyl, 4′-methoxyphenyl) were synthesized and subjected to reduction by the microorganisms Saccharomyces cerevisiae andGeotrichum candidum. Whereas the bioreduction of 3-methy-4-R-3-buten-2-ones afforded the corresponding (S)-4-R-3-methybutan-2-ones, the bioreduction of 3-chloromethyl- and 3-bromomethyl-4-R-3-buten-2-ones afforded the corresponding (R)-4-R-3-methybutan-2-ones.

Palladium-catalyzed domino cyclization (5-exo/3-exo), ring- expansion by palladium rearrangement, and aromatization: An expedient synthesis of 4-arylnicotinates from Morita-Baylis-Hillman adducts

Various 4-arylnicotinate derivatives were synthesized via a palladium-catalyzed cascade reaction of N-(2-bromoallyl)-N-cinnamyltosylamides in a one-pot procedure in good yields. The reaction involves a domino 5-exo/3-exo carbopalladation, ring-expansion b

Dimethyl sulfide-boron trihalide-mediated reactions of α,β-unsaturated ketones with aldehydes: One-pot synthesis of Baylis-Hillman adducts and α-halomethyl enones

The reactions of aldehydes with 3-buten-2-one (2) were conducted in the presence of BBr3·Me2S or BCl3·Me2S and then worked up with aqueous NaHCO3, affording the α-methylene aldol 3, α-halomethyl aldol 4 or 6, and α-halomethyl enones 5 or 7, respectively. In contrast, the reactions quenched with water gave the α-halomethyl enones 5 or 7 in high yields, while the work-up with an aqueous 10% trimethylamine gave the α-methylene aldol 3. The phenol 15 and half-acetal 16 were obtained from the reaction of p-nitrobenzaldehyde (1a) with cyclohexenone (10).

New C=C bond formation via nonstoichiometric titanium(IV) halide mediated vicinal difunctionalization of α,β-unsaturated acyclic ketones

(equation presented) X = Cl: 92%, ZIE > 99/1 X = Br: 85%, ZIE = 9/1 Highly stereoselective vicinal difuctionalization of α/β-unsaturated ketones for the synthesis of multifunctionalized trisubstituted alkenes is described. The new reaction employs titaniu

The Baylis-Hillman reaction: An expedient synthesis of (Z)-keto allyl bromides and chlorides

A simple and expedient synthesis of (Z)- keto allyl bromides and chlorides, from the Baylis-Hillman adducts is described.

An Aldol Reaction of Boron Enolates Generated by the 1,4-Addition of B-Br-9-BBN to α,β-Unsaturated Ketones. A Synthesis of α-Bromomethyl-α,β-unsaturated Ketones

α-Bromomethyl-α,β-unsaturated ketones can be prepared easily by the successive addition of α,β-unsaturated ketones and then aldehydes to B-bromo-9-borabicyclononane.