43057-55-2

Upstream product

• 22863-24-7 1-phenyl-3-methyl-1H-1,2,4-triazol-5-one 
• 100706-04-5 3-(2-phenyl-thiosemicarbazono)-butyric acid ethyl ester 
• 141-52-6 sodium ethanolate 
• 100-63-0 phenylhydrazine 
• 4792-54-5 ethyl pyruvate phenylhydrazone 
• 220437-87-6 5-ethoxycarbonyl-5-methyl-2-phenyl<1,2,4>triazolidine-3-thione 
• 13207-43-7 2-phenythiosemicarbazide 
• 43057-38-1 5-methyl-2-phenyl-1,2,4-triazolidine-3-thione 

Downstream Products

• 105907-23-1 5-ethylmercapto-3-methyl-1-phenyl-1H-[1,2,4]triazole 
• 107771-59-5 5-(2,4-dinitro-phenylsulfanyl)-3-methyl-1-phenyl-1H-[1,2,4]triazole 
• 43057-59-6 3-methyl-5-(methylsulfanyl)-1-phenyl-1,2,4-triazole 

Relevant academic research and scientific papers

1,2,4-Triazole derivatives inhibiting the human immunodeficiency virus type 1 (HIV-1) in vitro

A novel series of selective 1,2,4-triazole nonnucleoside reverse transcriptase inhibitors (NNRTIs) is described. In MT-4 cells compound, 4f inhibited human immunodeficiency virus type 1 (HIV-1) induced cytopathology at an 1C50 of 9.98 μM with a

Oxidation and rearrangement of 5-substituted 5- ethoxycarbonyl[1,2,4]triazolidine-3-thiones

The reaction of ethyl 2-(phenylhydrazono)alkanoates (1) with potassium thiocyanate in acetic acid affords 5-ethoxycarbonyl-substituted [1,2,4]triazolidine-3-thiones (3). Oxidation (KMnO4) converts 3 into 1- ethoxycarbonyl-2,3-dihydro-1H-[1,2,4]