43141-69-1Relevant academic research and scientific papers
Investigation of benzophenoxazine derivatives for the detection of latent fingerprints on porous surfaces
Alsolmy, Eman,Abdelwahab, Walid M.,Martinez, Vincent,Henary, Maged,Patonay, Gabor
, (2020/02/11)
In this report, two classes of benzophenoxazine dyes, Nile red and Nile blue derivatives, were evaluated for the detection of latent fingerprints on porous surfaces. The efficiency to develop fingerprints is influenced by the physical properties of the dye molecules including hydrophobicity as characterized by distribution coefficient value (logD), and other factors such as chemical structure of the dye and hydrogen bonds. Both Nile red and the basic form of Nile blue showed excellent to acceptable ability to detect fingerprints due to their great hydrophobicity at 515 and Crime Scene Search (CSS) settings of the forensic light source. Higher hydrophobicity derivatives of Nile red and Nile blue (in the basic form) improved both quality and sensitivity of fingerprint detection in comparison with their corresponding parent dyes. They developed strong luminescent and visible fingerprints, and a better contrast was achieved between impressions and the background surface suggesting the potential use of these compounds in forensic investigation. Therefore, the hydrophobic derivatives are considered dual-fingerprint reagents because the developed prints can be seen by the naked eye and under illumination process. However, lower hydrophobicity derivatives of Nile red and Nile blue and derivatives with different substituents developed weak or non-luminescent fingerprints with poor contrast. A complete analysis of what dye properties are the most important in fingerprint detection is discussed along with dye optimization for improved performance.
A N, N - dibutyl m-aminophenol preparation method
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Paragraph 0032-0035; 0036-0037; 039-0040; 0042-0049, (2019/07/01)
The invention belongs to organic synthesis and chemical raw material preparation technology field, in particular to N, N - dibutyl m-aminophenol of the preparation method, N, N - dibutyl m-aminophenol preparation including: (1) dinitrobenzene substituted benzyl alcohol generated by the reaction with 1 - benzyloxy - 3 - nitrophenyl; (2) 1 - benzyloxy - 3 - nitrobenzene with butyraldehyde in adding the acid to the acid substituted in the reaction solution, or, 1 - benzyloxy - 3 - nitrobenzene with butyraldehyde to replace the solvent of the reaction solution after the recovery of the organic solvent is soluble in the re-dissolved in the re-dissolved solution, by reducing amination and catalytic debenzylation of hydrogenation generating N, N - dibutyl m-aminophenol. 1 - Benzyloxy - 3 - nitrophenyl without separation and purification, directly with the butyral and a hydrogen reduction amination and debenzylation of hydrogenation reaction. The method is simple, mild condition, equipment strength requirement is low, not produce waste, environment friendly, easily available raw materials, high yield, is suitable for the large-scale production.
Inter-alkane amidogen phenolic synthetic method (by machine translation)
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, (2019/01/23)
Inter-alkane amidogen phenolic synthetic method, its characteristic is: 1st step, between the two alkane amidogen acyl aniline and sulfuric acid aqueous solution mixing and heating to 50 - 110 °C, thermal insulation reaction of aniline [...] sulfuric acid aqueous solution; 2nd step, continue to drip the sodium nitrite aqueous solution, sodium nitrite aqueous solution for dropping temperature of - 10 - 20 °C, drop bi yu 5 - 30 °C insulation, [...] aniline obtained diazonium salt of the sulfuric acid aqueous solution; 3rd step, [...] aniline diazonium salt of the sulfuric acid aqueous solution is directly heated to 45 - 110 °C, thermal insulation, in the hydrolysis reaction of the diazonium salt, cooling after treatment, to obtain the product between two alkane amidogen phenol; three-step required by the reaction of sulfuric acid in the 1st step reaction in the finished disposable adding; a three-step reaction in a finish step by step in the pot. The method of the invention with raw materials are cheap, abundant, synthetic high security of the process, the product yield is high, the three waste less pollution and the like, has high industrial value. (by machine translation)
Method for continuously synthesizing meta-di-alkane aminophenol
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Paragraph 0027; 0033; 0042, (2019/01/23)
The invention discloses a method for continuously synthesizing meta-di-alkane aminophenol. The technical scheme includes that continuous diazotization or continuous diazonium salt hydrolysis or continuous diazotization and diazonium salt hydrolysis is carried on raw materials such as di-alkane aminophenol, sodium nitrite and sulfuric acid, and after-treatment such as extraction is carried out to obtain the meta-di-alkane aminophenol which is a product. The method has the advantages that the raw materials can come from sufficient sources and are low in cost, processes for synthesizing the meta-di-alkane aminophenol are high in safety, products are high in yield, the method is little in waste gas, wastewater and industrial residue pollution, is green and environmental friendly and has a highindustrialization value, and the like.
Synthetic method for m-dialkylaminophenol
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Paragraph 0020, (2019/01/08)
The invention provides a synthetic method for m-dialkylaminophenol. The synthetic method is characterized by comprising the following steps: step 1, adding an aqueous solution of sodium nitrite into an aqueous solution of sulfuric acid containing m-dialkylaminoaniline drop by drop at a temperature of -10 to 20 DEG C, and maintaining the obtained solution at a temperature of 5 to 30 DEG C for 1 to10 h after completion of the addition so as to obtain an aqueous solution of sulfuric acid containing m-dialkylaminoaniline diazohydrosulfate; and step 2, directly heating aqueous solution of sulfuricacid containing m-dialkylaminoaniline diazohydrosulfate to 45-110 DEG C, maintaining the solution at the temperature for 1-18 h, allowing m-dialkylaminoaniline diazohydrosulfate to undergo the hydrolysis reaction of a diazonium salt, and successively carrying out cooling and post-treatment so as to obtain the product dialkylaminophenol, wherein sulfuric acid needed in the first step and the second step is totally added in one shot in a first-step reaction, and the first-step diazotization reaction and the second-step hydrolysis reaction of the diazonium salt are carried out step by step in one pot. The method of the invention has the characteristics of low raw material price, sufficient raw material sources, high safety, high product yield, less three-wastes pollution and the like, and has high industrialization value.
Photovoltaic Devices Prepared through a Trihydroxy Substitution Strategy on an Unsymmetrical Squaraine Dye
Wu, Jianglin,Si, Changfeng,Chen, Yao,Yang, Lin,Hu, Bin,Chen, Guo,Lu, Zhiyun,Huang, Yan
, p. 3234 - 3240 (2018/02/06)
A series of unsymmetrical arene-1,3-squaraine (USQ) derivatives with two, three, or four hydroxy (?OH) substituents, namely, USQ-2-OH, USQ-3-OH, or USQ-4-OH, respectively, were designed and synthesized, and the effect of the number of hydroxy groups on the optoelectronic properties of USQs were investigated. Despite the three compounds having similar UV/Vis absorption and HOMO energy levels, solution-processed bulk-heterojunction (BHJ) small-molecule organic solar cells with USQ-3-OH as electron-donor materials exhibit the highest power conversion efficiency of 6.07 %, which could be mainly attributed to the higher hole mobility and smaller phase separation. It is also noteworthy that the short-circuit current (Jsc) of the USQ-3-OH-based device is as high as 14.95 mA cm?2, which is the highest Jsc values reported for squaraine-based BHJ solar cells to date. The results also indicate that more ?OH substituents on squaraine dyes do not necessarily lead to better photovoltaic performance.
Preparation method of N,N-dibutyl m-aminophenol
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, (2018/10/19)
The invention relates to a preparation method of N,N-dibutyl m-aminophenol. The preparation method comprises the following steps: firstly, carrying out alkylation reaction on sodium m-aminobenzene sulfonate, a solvent, halohydrocarbon and an acid binding agent to obtain an alkylate solution, wherein the alkylation reaction temperature is 80 to 200 DEG C and the alkylation reaction time is 2 to 5 hours; secondly, mixing the alkylate solution with an alkaline reagent and water for carrying out alkali fusion reaction to obtain alkylated sodium phenolate, wherein the alkali fusion reaction temperature is 200 to 350 DEG C and the reaction time is 1 to 3 hours; then adding water; thirdly, carrying out acid precipitation reaction on the alkylated sodium phenolate and an acidic reagent for 0.5 to3 hours to obtain a crude product of the N,N-dibutyl m-aminophenol; fourthly, refining to obtain the N,N-dibutyl m-aminophenol. The N,N-dibutyl m-aminophenol prepared by the preparation method disclosed by the invention has the advantages of high yield, low cost, capabilities of reducing by-product types and post-treatment burden.
Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive 3,7-bis(dialkylamino)phenoxazin-5-ium derivatives
Ge, Jian-Feng,Arai, Chika,Kaiser, Marcel,Wittlin, Sergio,Brun, Reto,Ihara, Masataka
supporting information; experimental part, p. 3654 - 3658 (2009/04/06)
3,7-Bis(dialkylamino)phenoxazinium salts were synthesized and evaluated for in vitro activities against Plasmodium falciparum, Trypanosoma cruzi, T. brucei rhodesiense, and Leishmania donovani. Notably, the compounds showed potent antiprotozoal activities, especially against P. falciparum and T. cruzi. The compounds with alkyl side chains less than three carbons in length possessed good activities with high selective indices.
Improved functional group compatibility in the palladium-catalyzed synthesis of aryl amines
Harris, Michele C.,Huang, Xiaohua,Buchwald, Stephen L.
, p. 2885 - 2888 (2007/10/03)
(figure presented) The use of Pd2dba3 with bulky, electron-rich ligands 1 or 2 and LiN(TMS)2 as the base for the coupling of amines with aryl halides containing hydroxyl, amide, or enolizable keto groups is described. This protocol expands the utility of palladium-catalyzed C-N bond formation by allowing for the use of aryl halides containing these functional groups, obviating the need for protecting group manipulations.
Production of aminophenols
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, (2008/06/13)
A method of producing N,N-disubstituted aminophenols of the general formula STR1 wherein R1 and R2 are the same or different and each represents a saturated or unsaturated aliphatic hydrocarbyl, cycloalkyl, aralkyl, the phenyl ring of which may be further substituted, alkoxyalkyl, or a cycloalkylalkyl, except that R1 and R2 are not simultaneously methyl and R' represents hydrogen, halogen, nitro, cyano, alkyl or alkoxy, which comprises reacting an aminophenol of general formula STR2 wherein R3 represents hydrogen or R1, and R' is as defined above, with an organic halide species of general formula R2 X wherein R2 is as defined above and X is halogen under aqueous acidic conditions with the periodic addition of an acid trapping agent in such a way that continuous monitoring of pH is not required.
