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Cyclohexanenonanoic acid, also known as 1-cyclohexanepropanoic acid, is a synthetic organic compound with the chemical formula C??H??O?. It is a white crystalline solid that is soluble in organic solvents and has a molecular weight of 170.25 g/mol. This nine-carbon fatty acid is characterized by a cyclohexane ring attached to a three-carbon aliphatic chain, which includes a terminal carboxylic acid group. Cyclohexanenonanoic acid is used in various industrial applications, such as the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals, due to its unique structural properties that can influence the physical and chemical characteristics of the final products.

4352-53-8

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4352-53-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4352-53-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,5 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4352-53:
(6*4)+(5*3)+(4*5)+(3*2)+(2*5)+(1*3)=78
78 % 10 = 8
So 4352-53-8 is a valid CAS Registry Number.

4352-53-8Relevant academic research and scientific papers

Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity

Suzuki, Takayoshi,Ozasa, Hiroki,Itoh, Yukihiro,Zhan, Peng,Sawada, Hideyuki,Mino, Koshiki,Walport, Louise,Ohkubo, Rei,Kawamura, Akane,Yonezawa, Masato,Tsukada, Yuichi,Tumber, Anthony,Nakagawa, Hidehiko,Hasegawa, Makoto,Sasaki, Ryuzo,Mizukami, Tamio,Schofield, Christopher J.,Miyata, Naoki

, p. 7222 - 7231 (2013/10/21)

Histone Nε-methyl lysine demethylases KDM2/7 have been identified as potential targets for cancer therapies. On the basis of the crystal structure of KDM7B, we designed and prepared a series of hydroxamate analogues bearing an alkyl chain. Enzyme assays revealed that compound 9 potently inhibits KDM2A, KDM7A, and KDM7B, with IC50s of 6.8, 0.2, and 1.2 μM, respectively. While inhibitors of KDM4s did not show any effect on cancer cells tested, the KDM2/7-subfamily inhibitor 9 exerted antiproliferative activity, indicating the potential for KDM2/7 inhibitors as anticancer agents.

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