4387-16-0

Basic information

• Product Name: BIS(TRIMETHYLSILYL)BISPHENOL A
• Synonyms: 2,2-Bis(4'-trimethylsiloxyphenyl)propane;2,2-Bis[(4-trimethylsiloxy)phenyl]propane;2,2-Bis[(4-trimethylsilyloxy)phenyl]propane;Trimethyl[4-(1-methyl-1-(4-[(trimethylsilyl)oxy]phenyl)ethyl)phenoxy]silane;BIS(TRIMETHYLSILYL)BISPHENOL A
• CAS NO: 4387-16-0
• Molecular Formula: C₂₁H₃₂O₂Si₂
• Molecular Weight: 372.65
• Mol File: 4387-16-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 179°C 1,5mm
• Flash Point: 155.9°C
• Appearance: /
• Density: 0.959g/cm³
• Vapor Pressure: 1.09E-05mmHg at 25°C
• Refractive Index: 1.5178
• CAS DataBase Reference: BIS(TRIMETHYLSILYL)BISPHENOL A(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(TRIMETHYLSILYL)BISPHENOL A(4387-16-0)
• EPA Substance Registry System: BIS(TRIMETHYLSILYL)BISPHENOL A(4387-16-0)

Safety Data

• TSCA: No
• Hazardous Substances Data: 4387-16-0(Hazardous Substances Data)

Usage

General Description

Bis(trimethylsilyl)bisphenol A is a chemical compound with the formula (CH3)3Si2BPA. It is a silyl-protected derivative of bisphenol A, a widely used industrial chemical in the production of polycarbonate plastics and epoxy resins. The trimethylsilyl groups protect the hydroxyl groups on the bisphenol A molecule, making it more stable and less reactive. This makes bis(trimethylsilyl)bisphenol A useful as a precursor in the synthesis of various organic compounds, and as a protective agent for hydroxyl groups during chemical reactions. However, it is important to note that bis(trimethylsilyl)bisphenol A may pose health and environmental risks, and proper handling and disposal procedures should be followed.

InChI:InChI=1/C21H32O2Si2/c1-21(2,17-9-13-19(14-10-17)22-24(3,4)5)18-11-15-20(16-12-18)23-25(6,7)8/h9-16H,1-8H3

Upstream product

• 80-05-7 BPA 
• 10416-59-8 N,O-bis-(trimethylsilyl)-acetamide 
• 25561-30-2 N,O-Bis(trimethylsilyl)trifluoroacetamide 
• 10416-58-7 N,N-bis(trimethylsilyl)acetamide 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 80-05-7 BPA 
• 33073-28-8 2,2-Bis-(4-perfluorbutylsulfonyloxy-phenyl)-propan 

Relevant articles and documents

Assessment of Exposure to Di (2-ethylhexyl) Phthalate (DEHP) Metabolites and Bisphenol A (BPA) and Its Importance for the Prevention of Cardiometabolic Diseases

Exposomics analyses have highlighted the importance of biomonitoring of human exposure to pollutants, even non-persistent, for the prevention of non-communicable diseases such as obesity, diabetes, non-alcoholic fatty liver disease, atherosclerosis, and cardiovascular diseases. Phthalates and bisphenol A (BPA) are endocrine disrupting chemicals (EDCs) widely used in industry and in a large range of daily life products that increase the risk of endocrine and cardiometabolic diseases especially if the exposure starts during childhood. Thus, biomonitoring of exposure to these compounds is important not only in adulthood but also in childhood. This was the goal of the LIFE-PERSUADED project that measured the exposure to phthalates (DEHP metabolites, MEHP, MEHHP, MEOHP) and BPA in Italian mother–children couples of different ages. In this paper we describe the method that was set up for the LIFE PERSUADED project and validated during the proficiency test (ICI/EQUAS) showing that accurate determination of urinary phthalates and BPA can be achieved starting from small sample size (0.5 mL) using two MS techniques applied in cascade on the same deconjugated matrix.

Multicyclic poly(ether ketone)s obtained by polycondensation of 2,6,4′-Trifluorobenzophenone with various diphenols

2,6,4′-Trifluorobenzophenone (TFB) was polycondensed with silylated 4,4′-dihydroxybiphenyl (DHBP) or silylated bisphenol A in N-methylpyrrolidone by means of K2CO3 as catalyst and HF acceptor. At constant concentration (0.08 mol/L) t