4392-52-3

Upstream product

• 107-15-3 ethylenediamine 
• 98-09-9 benzenesulfonyl chloride 
• 98-10-2 benzenesulfonamide 
• 106-93-4 ethylene dibromide 
• 873-55-2 sodium benzenesulfonate 
• 1821-99-4 N,N'-bis(trimethylsilyl)ethylenediamine 

Downstream Products

• 101738-24-3 N,N'-(ethane-1,2-diyl)-bis(N-ethylbenzenesulfonamide) 
• 7250-99-9 1,4-bis(phenylsulfonyl)piperazine 
• 5451-44-5 N,N'-Di(phenylsulphonyl)hexahydro-1,4-diazepin 
• 60395-33-7 N,N'-(ethane-1,2-diyl)bis(N-methylbenzenesulfonamide) 
• 5131-37-3 1,3-dibenzenesulfonylimidazoline 
• 95035-96-4 N¹,N²-dibenzensulfonyl-N¹,N²-di(diethylaminoethyl)ethylenediamine 
• 120727-73-3 C₁₈H₂₄N₂O₆S₂ 
• 352031-14-2 1,3-diphenylsulfonyl-2-oxo-2-phenyl-1,3,2-diazaphospholidine 
• 344436-86-8 Pt(N(SO₂C₆H₅)CH₂CH₂N(SO₂C₆H₅))(P(C₆H₅)3)2*CH₂Cl₂ 
• 344425-31-6 N,N'-bis(benzenesulfonyl)ethylenediamido(1,5-cyclooctadiene)platinum(II) 
• 1189567-37-0 C₂₂H₂₈N₂O₆S₂ 
• 1190068-44-0 (N,N'-(ethane-1,2-diyl)dibenzenesulfonamido)(1,10-phenanthroline)copper(II) 
• 496039-67-9 1,2-bis-(benzenesulfonyl-benzyl-amino)-ethane 

Relevant academic research and scientific papers

(Dicyclopentadiene) platinum(II) dichloride: An efficient catalyst for the hydrosilylation reaction between alkenes and triethoxysilane

(Dicyclopentadiene) platinum(II) dichloride was found to be an efficient hydrosilylation catalyst (homogeneous) upon a wide variety of functionalized alkenes and alkenes terminated with chemical moieties (diphenyl amino-, N-carbazol- and N-isoindoline-1,3-dione-). It is noteworthy that the hydrosilylation of aminated alkenes with triethoxysilane exhibited the yield of over 70% and the selectivity (γ-isomer/β-isomer) of more than 3/1. Due to steric hindrance lowering Markovnikov probability, the alkenes with big terminal moieties (diphenyl amino-, N-carbazol- and N-isoindoline-1,3-dione-) presented the high ratio of anti-Markovnikov isomers. The strategy of the hydrosilylation of the protected diamino chelating alkene was developed.

Palladium-Catalyzed Modular Synthesis of Substituted Piperazines and Related Nitrogen Heterocycles

We report here a novel method for the modular synthesis of highly substituted piperazines and related bis-nitrogen heterocycles via a palladium-catalyzed cyclization reaction. The process couples two of the carbons of a propargyl unit with various diamine components to provide nitrogen heterocycles in generally good to excellent yields and high regio- and stereochemical control. (Chemical Equation Presented).

Efficient, solvent-free and rapid oxidation of alcohols to carbonyl compounds with N,N'-dibromo-N,N'-1,2-ethanediylbis(benzene sulfonamide)

N,N'-Dibromo-N,N'-1,2-ethanediylbis(benzene sulfonamide) (BNBBS): a safe, neutral and efficient reagent was utilized for the rapid and selective oxidation of alcohols to carbonyl compounds with no side reactions such as oxidations of carbon-hydrogen bonds, over oxidation of aldehydes and bromination of aromatic rings; under solvent-free condition, at room temperature with excellent yield.

Quantitative structure-activity relationships studies for prediction of antimicrobial activity of synthesized disulfonamide derivatives

A new series of disulfonamides were synthesized and assayed as antimicrobial agents against Staphylococcus aureus, Bacillus cereus, and Escherichia coli. The quantitative structure-activity relationship analysis (QSAR) was applied to find out the correlat

Synthesis and application of a microgel-supported acylating reagent by coupled ring-opening metathesis polymerization and activators Re-Generated by electron transfer for atom transfer radical polymerization

A novel microgel-supported acylating reagent (MGAR) was prepared by combining ring-opening metathesis polymerization (ROMP) and Activators Re-Generated by Electron Transfer for Atom Transfer Radical Polymerization (ARGET ATRP): (1) synthesis of an ATRP macroinitiator 3 by living ROMP of oxanorbornene-based activated ester 1, derived from Af-hydroxysuccinimide, using the Grubbs initiator RuCl2(PCy3)2(=CHPh) and (Z)-but-2-ene-l,4-diyl bis(2-bromopropanoate) (BDBP) as a terminating agent; (2) synthesis of MGAR 4 by ARGET ATRP of styrene (S) and divinylbenzene (DVB) using the prepared macroinitiator 3, a CuCI2ZMe6TREN (tris[2-(dimethylamino)ethyl]amine) catalyst system, a Sn(Oct)2 [tin(II)2ethylhexanoate] reducing agent. The synthesized microgels 4 exhibit excellent acyl (acetyl, benzoyl, phenylsulfonyl) transfer properties for primary and secondary amines (n-BuNH2, Et2NH, morpholine, etc.) under mild conditions (25 °C, 13.5-14 h) affording N-acylamines with high yield (95.6-100%) and purity (94.1-96.0%).

A novel and efficient solvent-free and heterogeneous method for the synthesis of primary, secondary and bis-N-acylsulfonamides using metal hydrogen sulfate catalysts

Some metal hydrogen sulfates were used as acid catalysts in the N-acylation of different sulfonamides using carboxylic acid chlorides and anhydrides as acylating agents under both heterogeneous and solvent-free conditions. Al(HSO4)3

N,N′-dibromo-N,N′-1,2-ethanediylbis (benzene sulfonamide) as a novel N-bromo reagent-catalyzed trimethylsilylation of alcohols and phenol with hexamethyldisilazane in both solution and solvent-free conditions

Preparation and catalytic application of N,N′-dibromo-N,N′ -1,2-ethanediylbis (benzene sulfonamide) for the trimethylsilylation of several of alcohols and phenols with hexamethyldisilazane in good to excellent yields under both solution and solvent-free c

Intramolecular catalysis of aminolysis of phosphorus heterocycles incorporating an α-aminoamide moiety. III. Synthesis of 2-oxo or 2-thioxo 1,3-disulfonyl-1,3,2-diazaphospholidines and reactions with amines and alcohols

A series of 2-oxo or 2-thioxo 1,3-disulfonyl-1,3,2-diazaphospholidines 4 was prepared by condensation of phosphonyl dichlorides 2 with bis-N,N′-sulfonylethylenediamines 1 in pyridine. Complete aminolysis or alcoholysis of heterocycles 4 took place with regeneration of sulfonyldiamines 1. These reactions are very sensitive to steric hindrance, and hydrolysis is generally favoured over aminolysis. The results are discussed in terms of mechanisms of phosphorylation.

N,N'-Doacylated imidazolidines and hexahydropyrimidines

A method for the preparation of N-monoacyl imidazolidines and hexahydropyrimidines (as hydrochlorides) by interaction of monoacylated derivatives of ethylenediamine and trimethylethylenediamine with chloromethyl methyl ether was developed.Also a method for the preparation of N,N'-diacylimidazolidines and hexahydropyrimidines either by acylation of their monoacyl derivatives or by reaction of the corresponding N,N'-diacyl alkylenediamine derivatives with dimethoxymethane, diacetoxymethane, 1,3,5-trioxane or chloromethyl methyl ether was designed. - Key words: N-mono- and N,N'-diacylated imidazolidines, N-mono- and N,N'-diacylated hexahydropyrimidines, N,N'-diacylated alkylenediamines, acylation, methylation, cyclization.