446-57-1 Usage
Uses
Used in Pharmaceutical Industry:
2,3-Difluorobenzyl chloride is used as an intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and medicines. Its role in the synthesis process is crucial for creating effective and safe medications.
Used in Agrochemical Industry:
In the agrochemical sector, 2,3-difluorobenzyl chloride is used as an intermediate in the production of agrochemicals, such as pesticides and herbicides. Its involvement in the synthesis of these chemicals helps to improve crop protection and yield.
Used in Organic Synthesis:
2,3-Difluorobenzyl chloride is used as a benzyl protecting group in organic synthesis reactions. This function is vital for the selective protection of certain functional groups during complex organic synthesis, allowing for the controlled formation of desired products.
Used in Fluorinated Compound Production:
As a building block for the production of fluorinated compounds, 2,3-difluorobenzyl chloride is instrumental in creating compounds with unique properties. These fluorinated compounds have applications in various fields, including materials science, chemical research, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 446-57-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,4 and 6 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 446-57:
(5*4)+(4*4)+(3*6)+(2*5)+(1*7)=71
71 % 10 = 1
So 446-57-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H5ClF2/c8-4-5-2-1-3-6(9)7(5)10/h1-3H,4H2
446-57-1Relevant academic research and scientific papers
Dibenzo seven-membered ring derivative as well as preparation method and application thereof
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Paragraph 0072; 0093-0094; 0099-0108, (2021/03/31)
The invention relates to a dibenzo seven-membered ring derivative as well as a preparation method and application thereof. The chemical structure of the dibenzo seven-membered ring derivative is shownas a formula (I), and X1 and X2 are respectively and independently selected from H, F, Cl, Br or I. The preparation method has easily available raw materials, and can ensure continuous supply and production; the raw materials are cheap and have the cost advantage; and thiophenol or sodium thiophenol is not used, so that the method is more environment-friendly and is also beneficial to the body health of related personnel. 7,8-difluorodibenzo[b,e]thiazepine-11(6H)-one as one of the products can further react to obtain 7,8-difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-ol, and the 7,8-difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-ol can be used as an important intermediate for preparing a drug baloxavir, so that baloxavir preparation cost is reduced.