4510-27-4

Upstream product

• 4510-49-0 N-(γ-Chlor-β-hydroxypropyl)diphenylamin 
• 122-39-4 diphenylamine 
• 106-89-8 epichlorohydrin 
• 168611-98-1 N-(2,3-dihydroxypropyl)diphenylamine 
• 65178-51-0 N-allyldiphenylamine 
• 3132-64-7 1,2-Epoxy-3-bromopropane 

Downstream Products

• 168611-98-1 N-(2,3-dihydroxypropyl)diphenylamine 
• 3297-76-5 1-phenyl-1,2,3,4-tetrahydroquinoline 
• 3297-75-4 3-hydroxy-1-phenyl-1,2,3,4-tetrahydroquinoline 
• 1067275-02-8 C₂₈H₃₃N₃O 
• 4510-28-5 1-amino-3-(diphenylamino)propan-2-ol 
• 112169-54-7 d,l-1-(N-isopropyl-N,N-dimethylamino)-3-diphenylaminopropan-2-ol iodide 
• 112169-53-6 [2-(4-Bromo-phenyl)-2-oxo-ethyl]-((S)-3-diphenylamino-2-hydroxy-propyl)-dimethyl-ammonium; bromide 
• 14503-72-1 d,l-1-diphenylamino-2-hydroxy-3-dimethylaminopropane 

Relevant academic research and scientific papers

Unique Domain for a Unique Target: Selective Inhibitors of Host Cell DDX3X to Fight Emerging Viruses

Emerging viruses like dengue, West Nile, chikungunya, and Zika can cause widespread viral epidemics. Developing novel drugs or vaccines against specific targets for each virus is a difficult task. As obligate parasites, all viruses exploit common cellular

Titanocene(III)-catalyzed conversion of N-(epoxyalkyl)anilines into indolines

Densely substituted indolines and azaindolines can be obtained by the titanocene(III) chloride catalyzed reductive opening of N-(oxiran-2-ylmethyl) anilines. The reaction optimization, substrate scope, and limitations are discussed, and a mechanistic pathway for the epoxideopening rearrangement is proposed. ARKAT-USA, Inc.

Titanocene(III)-catalyzed formation of indolines and azaindolines

(Chemical Equation Presented) Reductive cyclization of epoxides tethered to substituted anilines and aminopyridines in the presence of 3 mol % of titanocene dichloride and stoichiometric manganese metal promotes a radical annulation to form 3,3-disubstituted indolines and azaindolines.

Structure-activity relationship studies of the chromosome segregation inhibitor, Incentrom A

A series of Incentrom A analogs that inhibit the chromosome segregation process in yeast were synthesized and tested for their effects on chromosome stability and cell proliferation. Pharmacophore and structure-activity relationship of Incentrom A for the anti-yeast activity were established.

Synthesis and thermal reactions of N-(2,3-epoxypropyl)diphenylamine

The synthesis of N-(2,3-epoxypropyl)diphenylamine is reported. It was found that thermal opening of the oxirane ring of N-(2,3-epoxypropyl)diphenylamine occurred both at the secondary and the tertiary carbon atoms but the basic reaction product is 3-hydro

Enantioselective incorporation of carbon dioxide into epoxides catalyzed by optically active cobalt(II) complexes

The enantioselective chemical fixation of CO2 into an epoxide was developed using an optically active ketoimi-natocobalt(II) complex as a chiral Lewis acid. In the presence of a catalytic amount of the cobalt complex and amine base, enantioselective CO2 fixation with an epoxide proceeded with kinetic resolution to afford the corresponding carbonate along with unreacted epoxide, both of which were optically active. To improve their enantioselectivities, the ligand structures of the cobalt complexes and amine bases were examined. Thus, the optimized catalytic system was successfully applied to various epoxides to obtain the corresponding optically active cyclic carbonates and to recover epoxides with good-to-high enantioselectivities.