4513-41-1 Usage
Uses
Used in Pharmaceutical Research:
(E)-3-(2-chlorophenyl)prop-2-enoic acid is used as a key intermediate in the synthesis of pharmaceutical compounds due to its unique chemical structure and reactivity.
Used in Organic Synthesis:
In the field of organic synthesis, (E)-3-(2-chlorophenyl)prop-2-enoic acid is utilized as a building block for creating a variety of organic molecules, taking advantage of its reactive functional groups.
Used in Antioxidant and Anti-inflammatory Applications:
(E)-3-(2-chlorophenyl)prop-2-enoic acid is used as a potential therapeutic agent for its antioxidant and anti-inflammatory properties, which may be beneficial in the treatment of various diseases and conditions.
Used in Anticancer Applications:
(E)-3-(2-chlorophenyl)prop-2-enoic acid is used as a compound with potential anticancer properties, as it has been shown to inhibit the growth of cancer cells, making it a candidate for further research and development in oncology.
Used in Chemical Intermediates for Synthesis:
(E)-3-(2-chlorophenyl)prop-2-enoic acid is used as a chemical intermediate in the production of other compounds, leveraging its unique structure to facilitate the creation of new molecules with specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 4513-41-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,1 and 3 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4513-41:
(6*4)+(5*5)+(4*1)+(3*3)+(2*4)+(1*1)=71
71 % 10 = 1
So 4513-41-1 is a valid CAS Registry Number.
4513-41-1Relevant academic research and scientific papers
Acid- And base-switched palladium-catalyzed γ-C(sp3)-H alkylation and alkenylation of neopentylamine
Zhang, Jinquan,Zhang, Shuaizhong,Zou, Hongbin
supporting information, p. 3466 - 3471 (2021/05/31)
The functionalization of remote unactivated C(sp3)-H and the reaction selectivity are among the core pursuits for transition-metal catalytic system development. Herein, we report Pd-catalyzed γ-C(sp3)-H-selective alkylation and alkenylation with removable 7-azaindole as a directing group. Acid and base were found to be the decisive regulators for the selective alkylation and alkenylation, respectively, on the same single substrate under otherwise the same reaction conditions. Various acrylates were compatible for the formation of C(sp3)-C(sp3) and C(sp3)-C(sp2) bonds. The alkenylation protocol could be further extended to acrylates with natural product units and α,β-unsaturated ketones. The preliminary synthetic manipulation of the alkylation and alkenylation products demonstrates the potential of this strategy for structurally diverse aliphatic chain extension and functionalization. Mechanistic experimental studies showed that the acidic and basic catalytic transformations shared the same six-membered dimer palladacycle.
