4542-72-7

Basic information

• Product Name: 1,4-Bis(2-broMoethyl)benzene
• Synonyms: 1,4-Bis(2-broMoethyl)benzene
• CAS NO: 4542-72-7
• Molecular Formula: C₁₀H₁₂Br₂
• Molecular Weight: 292.01028
• Mol File: 4542-72-7.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,4-Bis(2-broMoethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Bis(2-broMoethyl)benzene(4542-72-7)
• EPA Substance Registry System: 1,4-Bis(2-broMoethyl)benzene(4542-72-7)

Safety Data

• Hazardous Substances Data: 4542-72-7(Hazardous Substances Data)

Usage

General Description

1,4-Bis(2-bromoethyl)benzene is a chemical compound with the molecular formula C10H12Br2. It is a white solid with a slight pleasant odor and is insoluble in water. 1,4-Bis(2-broMoethyl)benzene is commonly used as a building block in organic synthesis, particularly in the production of pharmaceuticals and specialty chemicals. It can also be used as a crosslinking agent in the manufacture of polymers and resins. 1,4-Bis(2-bromoethyl)benzene is considered to be moderately toxic and may cause skin and eye irritation upon contact. It is important to handle this chemical with care and follow proper safety protocols when working with it.

Upstream product

• 36076-25-2 (4-methoxycarbonylmethylphenyl)acetic acid methyl ester 
• 36076-26-3 diethyl 2,2'-(1,4-phenylene)diacetate 
• 5140-03-4 2-[4-(2-hydroxyethyl)phenyl]ethan-1-ol 

Downstream Products

• 857579-88-5 2,5-bis-(2-bromo-ethyl)-1,3-dinitro-benzene 
• 157254-60-9 1,4-PBIT dihydrobromide 
• 1047626-87-8 1,4-bis(2-azidoethyl)benzene 
• 857543-12-5 (4-carboxy-2,6-dinitro-phenyl)-acetic acid 
• 1633-22-3 [2.2]Paracyclophan 
• 2913-24-8 [3.3]paracyclophane 
• 78965-35-2 2,5-dibromo-1,4-bis(2-bromoethyl)benzene 
• 3998-55-8 1,4-Bis(2-mercaptoethyl)benzene 
• 130800-03-2 2,2'-(1,4-phenylene)diethyl diiodide 

Relevant articles and documents

Synthesis and characterization of a novel iNOS/Akt inhibitor Se,Se′-1,4-phenylenebis(1,2-ethanediyl)bisisoselenourea (PBISe)-against colon cancer

Our studies demonstrate that substitution of sulfur with selenium in known iNOS inhibitor increases the compound's potency by several folds in variety of different cancers cell lines tested. Hence, this approach may be used as a strategy to increase the e

SULFONIMIDAMIDE COMPOUNDS AS NLRP3 MODULATORS

Described herein are compounds of Formula (I), Formula (I-A), and Formula (I-B), solvates thereof, tautomers thereof, and pharmaceutically acceptable salts of the foregoing, Further described herein are methods of inhibiting NLRP3 using said compounds, and methods of and compositions useful in treating NLRP3-dependent disorders.

SULFONAMIDE DERIVATIVES AND USES THEREOF

The present disclosure relates to compounds of Formula (I) or (II): and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for inhibiting the maturation of cytokines of the IL-1 family by inhibiting inflammasomes and may be used in the treatment of disorders in which inflammasome activity is implicated, such as inflammatory, autoinflammatory and autoimmune diseases and cancers.