45529-92-8

Usage

Uses

Used in Pharmaceutical Industry:
4,5-dimethyloxazol-2-amine is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of novel drug candidates with improved therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 4,5-dimethyloxazol-2-amine is utilized as a building block in the creation of new agrochemicals, potentially enhancing crop protection and yield through innovative chemical formulations.
Used in Organic Chemistry Research:
4,5-dimethyloxazol-2-amine serves as a valuable compound in organic chemistry research, where it is employed to explore new synthetic pathways and develop advanced organic compounds with specific applications.
Used in Drug Discovery:
Due to its potential biological activities and pharmacological properties, 4,5-dimethyloxazol-2-amine is used in drug discovery processes to identify and optimize new lead compounds for various therapeutic areas.

InChI:InChI=1/C5H8N2O/c1-3-4(2)8-5(6)7-3/h1-2H3,(H2,6,7)

Upstream product

• 57-13-6 urea 
• 814-75-5 3-bromo-butanone 
• 21324-75-4 (4,5-dimethyl-oxazol-2-yl)-cyanamide 
• 420-04-2 CYANAMID 
• 513-86-0 3-hydroxy-2-butanon 
• 4091-39-8 3-chloro-2-butanone 

Downstream Products

• 191019-49-5 6-(4-Chloro-phenyl)-2,3-dimethyl-imidazo[2,1-b]oxazole 
• 729-99-7 sulphamoxole 
• 103640-72-8 bis-(N-acetyl-sulfanilyl)-(4,5-dimethyl-oxazol-2-yl)-amine 
• 110490-38-5 (4,5-dimethyl-oxazol-2-yl)-bis-(4-nitro-benzenesulfonyl)-amine 
• 35629-58-4 1-(3-chloro-phenyl)-3-(4,5-dimethyl-oxazol-2-yl)-urea 
• 35629-57-3 1-(2-chloro-phenyl)-3-(4,5-dimethyl-oxazol-2-yl)-urea 
• 35629-59-5 1-(4-chloro-phenyl)-3-(4,5-dimethyl-oxazol-2-yl)-urea 
• 35629-37-9 2-acetylamino-4,5-dimethyloxazole 

Relevant academic research and scientific papers

Oxazolyl pyrimidinone amide compound or medicinal salt thereof, preparation method and application of oxazolyl pyrimidinone amide compound or medicinal salt thereof

The invention discloses an oxazole pyrimidone amide compound or a pharmaceutically acceptable salt thereof, and a preparation method and application thereof. The oxazole pyrimidone amide compound has the following structural general formula (I) shown in the description, wherein R1 and R2 are respectively and independently selected from hydrogen and C1-3 alkyl, R3 is selected from C1-3 alkyl groups, R4 and R5 are independently selected from 5-6-membered aryl groups, the aryl groups are phenyl groups or heteroaryl groups containing 1-3 heteroatoms, the heteroatoms are selected from oxygen atoms or nitrogen atoms, and the heteroatoms are located at any position on the heteroaryl groups; the aryl is unsubstituted or at least substituted by one or more halogens or C1-3 alkyl groups, C1-3 polyhalogenated alkyl groups and C1-3 alkoxy groups. The invention also discloses an application of the compound as a TRPA1 antagonist, and the compound is used for preparing medicines for treating or preventing diseases, symptoms and/or obstacles regulated by TRPA1, such as pain and the like.

QUINOLINE DERIVATIVES

The invention concerns quinoline derivatives of Formula (I): or a pharmaceutically-acceptable salt thereof, wherein each of X1, p, R1, q, R2, R3, R4, R5, Ring A, r and R6 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders.

QUINAZOLINE DERIVATIVES

The invention concerns quinazoline derivatives of Formula (I) or a pharmaceutically-acceptable salt thereof, wherein each of X1, p, R1, q, R2, R3, R4, R5, Ring A, r and R6 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders.

QUINAZOLINE DERIVATIVES

The invention concerns quinazoline derivatives of Formula (I) or a pharmaceutically-acceptable salt, solvate or pro-drug thereof, wherein each of X1, p, R1, q, R2, R3, R4, R5, Ring A, r and R6 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders or in the treatment of disease states associated with angiogenesis and/or vascular permeability.

S-trifluorobutenyl derivatives and pesticidal uses thereof

S-trifluorobutenyl thiocarbonic acid esters of the formula STR1 and salts thereof, wherein X is R1 N or S and Y is RS or R3 R2 N; wherein R is a metal or a radical selected from alkyl, cycloalkylalkyl, halocycloalkylalkyl, alkenyl, haloalkyl, haloalkenyl, alkynyl, alkoxyalkyl, alkylthioalkyl, alkoxycarbonylalkyl, halophenoxyalkyl, trialkylsilylalkyl, (vinyl)dialkylsilylalkyl, (allyl)dialkylsilylalkyl, 2-chlorothiophene-5-ylmethyl, phenylalkyl, halophenylalkyl, nitrophenylalkyl, haloalkylphenylalkyl, dialkyl-2,3-dihydrobenzofuran-7-yl, [2-methyl-(1,1'-biphenyl)-3-yl]methyl, 3-phenoxybenzyl, phenylthioalkyl, halophenylthioalkyl, dialkylphosphoryl, dialkylthiophosphoryl, dialkylisoxazolylalkyl and thienylisoxazolylalkyl; wherein R1 is alkyl, cycloalkyl, cyano, dialkyl-2,3-dihydrobenzofuran-7-yl, halophenyl, halophenylalkyl, haloalkoxyphenyl, pyridinyl, halopyridinyl, alkyl-1,3,4-thiadiazolyl, haloalkyl-1,3,4-thiadiazolyl, benzothiazolyl, dialkyloxazolyl or thiazolinyl; wherein R2 is hydrogen or alkyl; and wherein R3 is alkyl, haloalkyl, cycloalkyl, cycloalkylalkyl, dialkylaminoalkyl, dialkyl-2-oxazolyl, 2-thiazolinyl, 2-benzothiazolyl, 4-phenyl-2-thiazolyl, alkyl-1,3,4-thiadiazolyl, haloalkyl-1,3,4-thiadiazolyl, pyridinyl, halopyridinyl, phenyl, halophenyl, halophenylalkyl, haloalkoxyphenyl, or dialkyl-2,3-dihydrobenzofuran-7-yl; provided that: when X is S, Y is R3 R2 N, when X is R1 N, Y is RS, R1 is other than alkyl and R is other than haloalkenyl; and when X is R1 N where R1 is CN and Y is RS, R is other than alkali metal. The compounds exhibit nematicidal and anthelmintic activity and are useful in agriculture and veterinary practice.