4583-58-8

Basic information

• Product Name: 2-Pentenoic acid, 5-hydroxy-5-phenyl-, methyl ester
• CAS NO: 4583-58-8
• Molecular Formula: C12H14O3
• Molecular Weight: 206.241
• Mol File: 4583-58-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Pentenoic acid, 5-hydroxy-5-phenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentenoic acid, 5-hydroxy-5-phenyl-, methyl ester(4583-58-8)
• EPA Substance Registry System: 2-Pentenoic acid, 5-hydroxy-5-phenyl-, methyl ester(4583-58-8)

Safety Data

• Hazardous Substances Data: 4583-58-8(Hazardous Substances Data)

Upstream product

• 80735-94-0 1-Phenyl-3-buten-1-ol 
• 292638-85-8 acrylic acid methyl ester 
• 100-52-7 benzaldehyde 
• 67-56-1 methanol 
• 3724-65-0 2-butenoic acid 
• 1117-71-1 methyl 4-bromocrotonate 
• 85636-50-6 1-(trimethylsiloxy)-1-methoxy-1,3-butadiene 
• 1117-71-1 methyl-4-bromo-2-butenoate 

Relevant articles and documents

Water-Compatible Synthesis of 2-Trifluoromethyl-1,3-Dioxanes

A water-compatible method for the diastereoselective synthesis of 2-trifluormethyl-1,3-dioxanes is described. The reaction proceeds under mild reaction conditions using simple inorganic bases; it has a very good substrate scope and can be performed with different Michael acceptors. Additionally, the reaction products can be further functionalized, showing an excellent perspective for future applications.

α,β-unsaturated δ-lactones from copper-catalyzed asymmetric vinylogous mukaiyama reactions of aldehydes: Scope and mechanistic insights

A direct regio-, diastereo-, and enantiocontrolled access to α,β-unsaturated δ-lactones is described, based on the reaction of a silyl dienolate and an aldehyde in the presence of 10% of Carreira's catalyst. The scope and limitations of this reaction, as well as mechanistic insights concerning the reactivity of an allyl copper species, are discussed.

REGIOSELECTIVE CONTROL OF ALLYL ANIONS WITH CADMIUM CHLORIDE: α vs. γ CONDENSATION WITH ALDEHYDES

A general method for directing the condensation of allyl anions such as 2 with aldehydes preferentially to the γ position of the unsaturated nucleophile is described.The procedure employs cadmium chloride to control the regioselectivity and will facilitat