460-36-6

Usage

Uses

Used in Air Conditioning and Refrigeration Industry:
1,1,1,3-Tetrafluoropropane is used as a refrigerant for air conditioning and refrigeration systems. It was introduced to replace harmful chlorofluorocarbons (CFCs) that were found to be responsible for the depletion of the ozone layer. Its use has been vital in the transition away from these harmful substances.
Used in Environmentally Friendly Alternatives:
1,1,1,3-Tetrafluoropropane is used as an environmentally friendly alternative to chlorofluorocarbons (CFCs) in various applications. Despite its lower ozone depletion potential compared to its predecessors, it is not completely environmentally harmless due to its high global warming potential.
However, due to its significant global warming potential, the use of 1,1,1,3-tetrafluoropropane is now being phased out in many countries in favor of substances with lower global warming potentials. This shift is aimed at reducing the overall environmental impact of refrigerants and promoting more sustainable solutions in the air conditioning and refrigeration industry.

InChI:InChI=1/C3H4F4/c4-2-1-3(5,6)7/h1-2H2

Upstream product

• 819-00-1 1,1-difluoro-1,3-dichloropropane 
• 503-66-2 3-hydroxypropionic acid 
• 690-27-7 2H-pentafluoropropene 
• 2816-43-5 triphenylgermane 
• 2240-88-2 3,3,3-Trifluoropropanol 

Downstream Products

• 460-73-1 1,1,1,3,3-Pentafluoropropane 
• 677-21-4 1,1,1-trifluoropropylene 

Relevant academic research and scientific papers

Versatile Reaction Pathways of 1,1,3,3,3-Pentafluoropropene at Rh(I) Complexes [Rh(E)(PEt3)3] (E=H, GePh3, Si(OEt)3, F, Cl): C-F versus C-H Bond Activation Steps

The reaction of the rhodium(I) complexes [Rh(E)(PEt3)3] (E=GePh3 (1), H (6), F (7)) with 1,1,3,3,3-pentafluoropropene afforded the defluorinative germylation products Z/E-2-(triphenylgermyl)-1,3,3,3-tetrafluoropropene and

Photochemical activation of SF6 by N-heterocyclic carbenes to provide a deoxyfluorinating reagent

The activation of the greenhouse gas SF6 using electron-rich N-heterocyclic carbenes gave 2,2-difluoroimidazolines or 2,2-difluoroimidazolidines as well as 2-thio derivatives of the carbene precursors. The N-heterocyclic carbenes can also convert SF4 to give similar products. The difluoroimidazolidine derivatives were applied in deoxyfluorination reactions. Furthermore, the activation of SF6 and the fluorination can be coupled in a one-pot process to convert 1-octanol into 1-fluorooctane.

REACTION OF HYDROXY AND CARBONYL COMPOUNDS WITH SULFUR TETRAFLUORIDE. X. REACTION OF ALIPHATIC β-HYDROXYCARBOXYLIC ACIDS WITH SULFUR TETRAFLUORIDE

The reactions of 3-hydroxypropionic, d,l-3-hydroxybutyric, d,l-4,4,4-trifluoro-3-hydroxybutyric, and 4,4,4-trifluoro-3-trifluoromethyl-3-hydroxybutyric acids with sulfur tetrafluoride were investigated.It was shown that the electronic nature of the substituents at the β-carbon atom has a significant effect on the direction of the reactions of β-hydroxycarboxylic acids with sulfur tetrafluoride.

REACTIONS OF CHLORINE MONOFLUORIDE. SUBSTITUTION OF CHLORINE ATOMS BY FLUORINE IN CHLORINE-SUBSTITUTED ALKANES AND ESTERS

In anhydrous hydrogen fluoride under mild conditions chlorine monofluoride selectively substitutes the chlorine atoms in chlorine-substituted alkanes and esters by fluorine with the formation of high yields of the corresponding fluorides.The presence of an alkoxycarbonyl group or difluoromethylene group at the α position to the CHCl group deactivates the chlorine atom, and substitution by fluorine does not occur.In chloroalkanes, from which elimination of the chloride ion leads to sufficiently stable carbocations, substitution by fluorine can be realized in the absence of hydrogen fluoride at temperatures between -20 and -60 deg C.The fluorinating capacity of chlorine monofluoride is increased in the presence of catalytic amounts (3-5percent) of antimony pentachloride.Here the reaction is less selective than in hydrogen fluoride.In certain cases substitution is accompanied by hydride transfers.