4607-84-5

Usage

Chemical structure

A cyclopropane ring with a benzoylamino group attached to it.

Derivative

It is a derivative of cyclopropane carboxylic acid.

Application

Used in organic synthesis and medicinal chemistry.

Pharmaceutical potential

May have potential pharmaceutical applications due to its unique structure and properties.

Building block

Can be used as a building block in the synthesis of various organic molecules and pharmaceuticals.

Structural interest

Its cyclopropane ring makes it structurally interesting.

Biological activity

The cyclopropane ring may contribute to its biological activity.

Field of relevance

A valuable compound in the field of organic chemistry and drug development.

Upstream product

• 3200-80-4 (Z)-1-amino-2-phenylcyclopropanecarboxylic acid 
• 98-88-4 benzoyl chloride 
• 63140-84-1 (Z)-5-benzylthio-1-phenyl-7-oxo-6-thia-4-azaspiro<2.4>hept-4-ene 
• 86557-47-3 (Z)-4-benzylidene-2-benzylthio-5(4H)-thiazolone 
• 15732-43-1 (E)-2-phenyl-4-benzylidene-5(4H)-oxazolone 
• 87378-79-8 methyl (Z)-1-<1-(N-imidazolyl)benzylideneamino>-2-phenylcyclopropanecarboxylate 
• 70315-54-7 methyl 1-benzamido-2-phenyl-cyclopropanecarboxylate 
• 4525-04-6 (Z)-(1,5-diphenyl)-7-oxo-6-oxa-4-azaspiro<2.4>hept-4-ene 
• 87378-72-1 methyl trans-2-phenyl-1-benzamido-cyclopropane-1-carboxylate 
• 4525-04-6 (E)-(1,5-diphenyl)-7-oxo-6-oxa-4-azaspiro<2.4>hept-4-ene 
• 842-74-0 4-benzylidene-2-phenyloxazole-5(4H)-one 
• 4525-04-6 (Z)-1,5-diphenyl-6-oxa-4-azaspiro<2.4>hept-4-en-7-one 

Downstream Products

• 70315-54-7 methyl 1-benzamido-2-phenyl-cyclopropanecarboxylate 

Relevant academic research and scientific papers

Reaction of 4-Methylene-5(4H)-oxazolones With Diazomethane

The reaction of diazomethane with some (E) and (Z)-2-substituted-4-methylene-5(4)-oxazolones (1a-c) under two different conditions, has been studied. (E) and (Z)-1,2-disubstituted-7-oxo-6-oxa-4-azaspiro-hept-4-enes (3a-c, 4a-c) were mainly obtained, together with multiple addition compounds.The reaction showed to be stereoselective only when the substituents were aromatic.Acid hydrolysis of compounds 3a and 4a produced a mixture of (E) and (Z)-3,5-disubstituted-tetrahydrofuran-2-ones (8a, 9a).Smooth methanolysis of the ring led to (E) and (Z)-1-benzamido-cyclopropanecarboxylic esters (10a-c, 11a-c), which, on acid hydrolysis, gave (E) and (Z)-1-amino-2-phenylcyclopropanecarboxylic acids 12a and 13a.The pmr spectra have been analyzed by an iterative computer method, and the computed best values obtained have been used to deduce the stereochemistry of the spiroderivatives.