15732-43-1Relevant academic research and scientific papers
Synthesis of 3-Amino-6,7-Dihydroferroceno[a]Quinolizin-4-One Derivatives via the Reaction of 3,4-Dihydroferroceno[c]Pyridines with Azlactones
Shuvalov, Vladislav Yu.,Rozhkova, Yuliya S.,Plekhanova, Irina V.,Kostyuchenko, Anastasia S.,Shklyaev, Yurii V.,Fisyuk, Alexander S.
, p. 7 - 14 (2022/02/25)
[Figure not available: see fulltext.] Derivatives of 3-amino-6,7-dihydroferroceno[a]quinolizin-4-one were obtained by the reaction of 3,4-dihydroferroceno[c]pyridines with 4-(ethoxymethylidene)- and 4-(3-oxo-2-benzofuran-1(3H)-ylidene)-2-phenyl-1,3-oxazol-5(4H)-ones (azlactones) in moderate to good yields. The intermediate products of the addition of 4-(ethoxymethylidene)-2-phenyl-1,3-oxazol-5(4H)-one to the alkyl group of 1-alkyl-3,4-dihydroferroceno[c]pyridines were isolated and characterized. The reaction of 4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one with 3,4-dihydroferroceno[c]pyridines led to the formation of derivatives of 3-amino-2-phenyl-3,4,6,7-tetrahydroferroceno[a]quinolizin-4-one, which were oxidized with DDQ to 3-amino-2-phenyl-6,7-dihydroferroceno[a]quinolizin-4-one.
Practical synthesis of 4-benzylidene-2-phenyl-5(4H)-oxazolones
Siddaiah,Basha, G. Mahaboob,Sudhakar,Srinuvasarao,Kumar, Y. Santosh
supporting information, p. 2191 - 2197 (2013/07/25)
A simple and alternative method has been developed for the synthesis of 4-benzylidene-2-phenyl-5(4H)-oxazolones via reactions of hippuric acid with various aldehydes in the presence of 2-chloro-4,6-dimethoxy-1,3,5-triazine/N- methylmorpholine at 75 °C. Co
Benzylidene-oxazolones as molecular photoswitches
Blanco-Lomas, Marina,Campos, Pedro J.,Sampedro, Diego
, p. 4334 - 4337 (2012/10/29)
The synthesis and photochemical study of a family of molecular switches inspired by the green fluorescent protein (GFP) chromophore is presented. These compounds can be easily synthesized, and their photophysical properties may be tuned. Due to their effi
Comparison of clinoptilolite, analcime and yugawaralite for synthesis of unsaturated 5(4H)-oxazolones in solvent-free condition and microwave irrudiation
Fozooni, Samieh,Tikdari, Ahmad Momeni,Hamidian, Hooshang
, p. 77 - 82 (2008/09/20)
In view of the importance of azlactones as synthons, biological importance of the compounds and the advantages offered by coupling microwave activation with dry media reactions, we report here a solvent-free procedure for the synthesis of 2-phenyl-5(4H)-o
Oxazolone analogs as amyloid aggregation inhibitors and for the treatment of alzheimer's disease and disorders related to amyloidosis
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, (2008/06/13)
Disclosed are compounds of the Formula I and their use in a method of inhibiting the aggregation of amyloid proteins and in a method of imaging amyloid deposits.
Reactions of 2-aryl-4-arylidene-4H-oxazol-5-ones with 3-amino-1,2,4- triazole, 5-aminotetrazole, and 2-aminobenzimidazole
Chebanov,Desenko,Kuzmenko,Borovskoy,Musatov,Sadchikova
, p. 2845 - 2849 (2007/10/03)
The reactions of 3-amino-1,2,4-triazole, 5-aminotetrazole, and 2-aminobenzimidazole with 2-aryl-4-arylidene-4H-oxazol-5-ones (azlactones) were studied. The electron-releasing properties of the azole ring were demonstrated to influence the reaction pathway
Synthesis of 4-arylidene-2-phenyloxazol-5-ones using 1:1 mixture of Al2O3-H3BO3
Kashyap, Jyotimoni,Chetry,Das, Pranab J.
, p. 4187 - 4191 (2007/10/03)
Cyclodehydration-condensation of hippuric acid and arylaldehydes have been carried out using a 1:1 mixture of Al2O3-H3BO3 in the presence of stoichiometric quantity of acetic anhydride to give the target compoun
(Z)- and (E)-2-Phenyl-4-benzylidene-5(4H))oxazolones as Dienophiles. Improved Selectivity by the Use of Heterogeneous Catalysts
Cativiela, Carlos,Garcia, Jose I.,Mayoral, Jose A.,Pires, Elisabet,Brown, Robert
, p. 9217 - 9222 (2007/10/02)
Silica gel treated with AlEt2Cl or TiCl4 efficiently promotes the reaction of cyclopentadiene with (Z)-2-phenyl-4-benzylidene-5(4H)-oxazolone (1a) with very little Z/E isomerization.Silica gel treated with TiCl4 and ZnCl2 supported on silica gel leads to
A convenient synthesis of fungitoxic 1,3,4-oxadiazolopyrimidin-5-ones through Michael addition followed by ring transformation
Yadav, L. D. S.,Tripathi, R. K.,Dwivedi, R.,Shukla, S. N.,Singh, H.
, p. 565 - 568 (2007/10/03)
Michael-type addition of 2-amino-5-aryl-1,3,4-oxadiazoles (1a-d) to 4-benzylidene-5-oxazolones (2a-c) followed by intramolecular ring transformation of the resulting adducts (3a-l) yield new bicyclic compounds, 2,7-diaryl-6-benzamido-6,7-dihydro-5H-1,3,4-oxadiazolopyrimidin-5-ones (4a-l) in one pot.The products (4a-l) have been compared with Dithane M-45, a commercial fungicide, for their fungitoxicity against H. oryzae and C. saccharii.Based on screening data a possible structure-activity relationship has been suggested.
Compounds having an aryltriazine structure
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, (2008/06/13)
A compound having an aryltriazine structure selected from those of formula (I): STR1 for which the meaning of the substituents Ar, R1, R5, R6, and R6 ' is given in the description. The compound of the invention is useful as medicinal product for disorders associated with a cholinergic dysfunction.
