15192-76-4Relevant articles and documents
Development, evaluation and effect of anionic co-ligand on the biological activity of benzothiazole derived copper(II) complexes
Bandyopadhayaya, Shreetama,Bhar, Kishalay,Jain, Surbhi,Mandal, Chandi C.,Sharma, Anuj K.,Singh, Vikas K.,Tapryal, Suman
, (2020)
Research on development of novel metal based anti-cancer agents continues with its popularity among bioinorganic community. Benzothiazole, an important heterocyclic pharmacophore, was chosen as a valuable and useful scaffold for the synthesis of novel copper(II) complexes. Three new copper(II) complexes obtained from the synthesis of newly synthesized benzothiazole based N-(benzo[d]thiazol-2-ylmethyl)-N-methyl-2-(pyridin-2-yl)ethan-1-amine (btzpy) ligand with CuCl2 [Cu(btzpy)Cl2] (1), Cu(NCS)2 [Cu(btzpy)(NCS)2] (2), and Cu(NO3)2 [Cu(btzpy)(NO3)(H2O)]NO3 (3) were isolated and characterized by physical and spectroscopic measurements, including single-crystal X-ray structures. The interaction of complexes 1 and 3 with calf thymus (CT)-DNA was investigated using ethidium bromide fluorescence quenching assay and weak intercalation with KSV values of 9.8 × 102 M?1 and 8.2 × 102 M?1, respectively was observed. All three complexes have shown DNA cleavage of supercoiled plasmid DNA forming single nicked and double nicked forms in the presence of external reducing agents like 3-mercaptopropionic acid (3-MPA) and ascorbic acid. The water-soluble complexes 1 and 3 also show prominent hydrolytic DNA cleavage. From the DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging assay, it was observed that complex 2 also exhibits good antioxidant properties. The cytotoxicity of complexes 1–3 was tested against the lung cancer cell line (A549) and complex 2 with -NCS moiety shows maximum activity in the micromolar range. A rationale for the observed activity is proposed in light of the other properties of these molecules.
Davis, T. L.
, p. 2153 - 2156 (1936)
Oxidation of phenyl propyne catalyzed by copper(II) complexes of a benzimidazolyl schiff base ligand: Effect of acid/base, oxidant, surfactant and morphology
Kumar, Ravinder,Mathur, Pavan
, p. 818 - 823 (2015)
Copper(II) complexes with a new N-Substituted benzimidazolyl schiff base ligand are used as catalyst for the oxidation of 1-phenyl propyne. The oxidation is carried out under mild conditions using stoichiometric amounts of oxidant and catalytic amounts of Cu(II) complex as catalyst. Effect of acid/base, oxidant, morphology and surfactant has been studied. Two major products of phenyl propyne oxidation are the α-diketonic product and a terminal aldehyde. Diketone is the major product under acidic conditions while aldehyde formation is highest under basic conditions. The maximum conversion is found with the NO3- bound complex. GC-MS is used to find the percentage yields of products. SEM and PXRD of the reused complexes as catalyst suggest that morphology affects the catalytic efficiency.
Copper(II) complexes with box or flower type morphology: Sustainability versus perishability upon catalytic recycling
Kumar, Ravinder,Yadav, Anjana,Mahiya, Kuldeep,Mathur, Pavan
, p. 279 - 284 (2016)
Graphical abstract Selective oxidation of p-chlorobenzyl alcohol to p-chlorobenzaldehyde is carried out by new copper(II) complexes of a benzimidazolyl schiff base ligand. Efficiency of oxidation depends on the morphology of the complexes; box type morphology sustains catalysis upon recycling to a greater extent in comparison to the flower type.
Synthesis and spectral studies of copper complexes using a N-octylated bis benzimidazole diamide ligand
Mohapatra, Subash Chandra,Mathur, Pavan
, p. 612 - 616 (2011)
Monomeric Cu(II) and Cu(I) complexes bound to a tetradentate bis-benzimidazole diamide ligand N,N′-bis(N-octyl benzimidazolyl-2yl) (methyl)pentane diamide (O-GBGA) have been isolated and characterized. X-Band EPR spectra of the copper(II) complexes in CH
Facile synthesis of a hierarchical CuS/CuSCN nanocomposite with advanced energy storage properties
Kannangara, Yasun Y.,Prabunathan, Pichaimani,Song, Jang-Kun
, p. 15387 - 15396 (2018/09/29)
We introduce CuS/CuSCN nanocomposites as active materials in pseudocapacitors, in which the redox reactions of both CuS and CuSCN simultaneously contribute to energy storage. This nanocomposite is prepared using an in situ methodology via facile, low-energy-consuming green nanochemistry. The CuS/CuSCN nanocomposites offer a high capacitance compared to their individual constituents. CuS nanorods (～15 nm) are anchored on the surface of CuSCN nanosheets (～100 nm) and they interconnect the CuSCN nanosheets, producing mesoporous nanoclusters with a large surface area, thus improving the charge transfer efficiency. The CuS/CuSCN nanocomposites exhibit high electrical conductivity and strong redox reactivity, and in particular, the pseudocapacitor with a compositional ratio of 1:1 exhibits the highest charge transfer efficiency. Consequently, the 11 CuS/CuSCN active material exhibits a high energy density (approximately 63 W h kg-1) and a high power density (1.9 kW kg-1 at 9.0 W h kg-1) as a single electrode. The highest specific capacitance is measured to be 1787.3 F g-1 in the single electrode. Furthermore, an aqueous asymmetric hybrid supercapacitor based on the CuS/CuSCN 1:1//activated carbon (AC) shows an approximately four times increase in the power density (7.9 kW kg-1), compared to the single electrode.
