4670-17-1

Basic information

• Product Name: 3,5-DIMETHOXY-PHTHALIC ANHYDRIDE
• Synonyms: 3,5-DIMETHOXY-PHTHALIC ANHYDRIDE;4,6-Dimethoxy-1,3-isobenzofurandione
• CAS NO: 4670-17-1
• Molecular Formula: C₁₀H₈O₅
• Molecular Weight: 208.16752
• Mol File: 4670-17-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 403.9°C at 760 mmHg
• Flash Point: 184.9°C
• Appearance: /
• Density: 1.382
• Vapor Pressure: 9.84E-07mmHg at 25°C
• Refractive Index: 1.564
• CAS DataBase Reference: 3,5-DIMETHOXY-PHTHALIC ANHYDRIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIMETHOXY-PHTHALIC ANHYDRIDE(4670-17-1)
• EPA Substance Registry System: 3,5-DIMETHOXY-PHTHALIC ANHYDRIDE(4670-17-1)

Safety Data

• Hazardous Substances Data: 4670-17-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H8O5/c1-13-5-3-6-8(7(4-5)14-2)10(12)15-9(6)11/h3-4H,1-2H3

Upstream product

• 2150-37-0 methyl 3,5-dimethoxybenzoate 
• 63585-71-7 4,6-dimethoxy-3-trichloromethyl-1-benzo[c]furanone 
• 1132-21-4 3,5-dimethoxybenzoic acid 
• 76697-63-7 4,6-Dimethoxyphthalid-3-carbonsaeure 
• 58545-97-4 4,6-dimethoxy-phthalide 
• 72003-92-0 catenarin tetramethyl ether 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 13133-05-6 3,5-dimethoxyphthalic acid 

Downstream Products

• 17846-92-3 cis-2-Propen-⁽¹⁾-yl-4.6-dimethoxy-benzoesaeuremethylester 
• 100117-90-6 2,4-dimethoxy-6-ξ-propenyl-benzoic acid 
• 17924-91-3 2,4-Dimethoxy-6-(E-prop-1-enyl)benzoic acid 
• 17846-93-4 2-Propin-⁽¹⁾-yl-4.6-dimethoxy-benzoesaeure 
• 17947-63-6 2-Propin-⁽¹⁾-yl-4.6-dimethoxy-benzoesaeuremethylester 
• 17846-90-1 methyl 2-formyl-4,6-dimethoxybenzoate 
• 54130-71-1 2-(2-hydroxy-4-methyl-benzoyl)-3,5-dimethoxy-benzoic acid 
• 5018-84-8 emodin-6,8-di-O-methyl ether 
• 144828-20-6 3,5-dimethoxy-2-(4-hydroxy-3-methylbenzoyl)benzoic acid 

Relevant articles and documents

Design, Synthesis, Molecular Docking, and Biological Evaluation of New Emodin Anthraquinone Derivatives as Potential Antitumor Substances

The emodin anthraquinone derivatives are generally used in traditional Chinese medicine due to their various pharmacological activities. In the present study, a series of emodin anthraquinone derivatives have been designed and synthesized, among which 1,3-dihydroxy-6,8-dimethoxyanthracene-9,10-dione is a natural compound that has been synthesized for the very first time, and 1,3-dimethoxy-5,8-dimethylanthracene-9,10-dione is a compound that has never been reported earlier. Interestingly, while total seven of these compounds showed neuraminidase inhibitory activity in influenza virus with inhibition rate more than 50 %, specific four compounds exhibited significant inhibition of tumor cell proliferation. The further results demonstrate that 1,3-dimethoxy-5,8-dimethylanthracene-9,10-dione showed the best anticancer activity among all the synthesized compounds by inducing highest apoptosis rate to HCT116 cancer cells and arresting their G0/G1 cell cycle phase, through elevation of intracellular level of reactive oxygen species (ROS). Moreover, the binding of 1,3-dimethoxy-5,8-dimethylanthracene-9,10-dione with BSA protein has thoroughly been investigated. Altogether, this study suggests the neuraminidase inhibitory activity and antitumor potential of the new emodin anthraquinone derivatives.

Synthesis and biological activity of new phthalimides as potential anti-inflammatory agents

The overproduction of nitric oxide (NO) plays an important role in a variety of pathophysiological processes, including inflammation. Therefore, the suppression of NO production is a promising target in the design of anti-inflammatory agents. In the prese