4694-12-6

Usage

Uses

Used in Fragrance and Flavoring Industry:
2,4,4-Trimethylcyclopentanone is utilized as a key ingredient in the production of fragrances and flavorings due to its agreeable scent, enhancing the sensory experience of various consumer products.
Used in Pharmaceutical Synthesis:
In the pharmaceutical sector, 2,4,4-Trimethylcyclopentanone serves as an intermediate in the synthesis of various medicinal compounds, contributing to the development of new drugs and therapies.
Used in Agricultural Chemicals:
2,4,4-TRIMETHYLCYCLOPENTANONE also plays a role in the agricultural industry, where it is used as an intermediate in the synthesis of agricultural chemicals, supporting crop protection and enhancement strategies.
Used in Insect Repellent Formulations:
Capitalizing on its insect repellent properties, 2,4,4-Trimethylcyclopentanone is employed as a potential ingredient in insect repellent products, offering a natural alternative for pest control and protection against insect-borne diseases.

InChI:InChI=1/C8H14O/c1-6-4-8(2,3)5-7(6)9/h6H,4-5H2,1-3H3/t6-/m1/s1

Upstream product

• 10276-21-8 isophorone oxide 
• 109-63-7 trifluoroborane diethyl ether 
• 71-43-2 benzene 
• 4694-17-1 5,5-dimethlycyclohex-2-en-1-one 
• 126-81-8 dimedone 
• 17530-69-7 3-chloro-5,5-dimethylcyclohex-2-en-1-one 
• 3937-59-5 2,4,4-trimethyl-adipic acid 
• 10275-88-4 (+/-)-1,4,4-trimethyl-2-oxo-cyclopentanecarbaldehyde 
• 74675-97-1 (2,4-Dimethyl-1-methylene-pent-4-enyloxy)-trimethyl-silane 
• 7647-01-0 hydrogenchloride 
• 7664-93-9 sulfuric acid 
• 861573-63-9 1-hydroxy-2,4,4-trimethyl-cyclopentanecarboxylic acid 
• 53685-71-5 3,3-dimethyl-adipic acid diethyl ester 
• 116-02-9 3,3,5-trimethylcyclohexanol 

Downstream Products

• 19265-05-5 1,1,3-trimethyl glutaric acid 
• 597-43-3 2,2-dimethylsuccinic acid 
• 4694-11-5 2,2,4,4-tetramethylcyclopentanone 
• 6949-23-1 4-methyl-3-nitrobenzenesulfonamide 
• 129958-40-3 N-(4-methyl-3-nitrobenzenesulfonyl)-1,3,3-trimethylcyclobutanecarboximidate 
• 129958-42-5 N-(3,5,5-trimethyl-2-methoxy-2-cyclopentenyl)-4-methyl-3-nitrobenzenesulfonamide 
• 129958-41-4 N-(1,4,4-trimethyl-2-methoxy-2-cyclopentenyl)-4-methyl-3-nitrobenzenesulfonamide 
• 53907-60-1 cyclopentane, 1,1,3,4-tetramethyl-, cis- 
• 50876-33-0 1,1,3,3-tetramethyl-cyclopentane 
• 104461-75-8 1,4,4-Trimethyl-2-oxo-cyclopentanecarboxylic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 20309-77-7 trans-1,1,3,4-Tetramethyl-cyclopentan 
• 65378-76-9 1,2,4,4-tetramethylcyclopentene 
• 65378-77-0 1,3,3,5-Tetramethyl-cyclopenten-⁽¹⁾ 

Relevant academic research and scientific papers

Synthesis of pseudoiridolactones

Bicyclic δ-lactones with a carbon group at the bicyclic junction C-7a, designed as pseudoiridolactones, were synthesized from α-alkyl-α-hydroxymethylcyclopentanones via an intramolecular Horner-Wadsworth-Emmons reaction.

Solid-acid catalysed rearrangement of cyclic α,β-epoxy ketones

Various cyclic α,β-epoxy ketones rearranged to α-formyl ketones and/or vicdiones in the presence of catalytic amounts of zeolites and montmorillonite K10. This provides an excellent alternative to conventional homogeneous systems with respect to yields and workup. Differences in product distribution and type of products in the rearrangement of pulegone oxide could be reasonably explained by invoking different pathways for homogeneous and heterogeneous catalysts.

IMPROVED SYNTHESIS OF 2-HYDROXY-4,4,6-TRIMETHYL-2,5-CYCLOHEXADIENONE, USEFUL AS A FLAVORING ADDITIVE

The title dienone 1, useful for modification, improvement or increasing organoleptic properties of tobacco, sucrose syrups, flavored beverages, was prepared in 40-55percent overall yield from isophorone, by chlorination of 2-hydroxy-isophorone (2), rearrangement into 6-chloro-2-hydroxyisophorone (5) and dehydrochlorination.An excellent yield of 3-chloro-2-hydroxy-4,4,6-trimethyl-2,5-cyclohexenone (12) was obtained by chlorination of 5 followed by dehydrohalogenation.

On the Intramolecular Reactivity of Azidoenones

The thermally induced intramolecular eliminative rearrangements of 2--2-cycloalkenones are described.