471903-19-2

Usage

Chemical structure

An organic compound derived from cyclohexene carboxylic acid with a methyl ester group, hydroxyl group, sulfonamide, and chlorophenyl substituents.

Functional groups

Contains a carboxylic acid, ester, hydroxyl, sulfonamide, and aromatic groups.

Molecular weight

Approximately 411.83 g/mol

Appearance

Likely a solid or viscous liquid, depending on the conditions.

Solubility

Soluble in organic solvents such as ethanol, methanol, and acetone.

Stability

Stable under normal temperature and pressure, but sensitive to heat, light, and moisture.

Reactivity

Can undergo reactions such as esterification, hydrolysis, and nucleophilic substitution.

Biological activity

Has potential applications in the pharmaceutical industry as a sulfonyl derivative with potential biological activity.

Safety

Should be handled and used in accordance with proper safety measures and regulations for handling and disposal of hazardous chemicals.

Upstream product

• 470716-51-9 2-[[(4-chlorophenyl)sulfonyl]methyl]-1,4-difluorobenzene 
• 292638-85-8 acrylic acid methyl ester 
• 85117-99-3 2-(bromomethyl)-1,4-difluorobenzene 
• 470716-52-0 2-[[(4-chlorophenyl)thio]methyl]-1,4-difluorobenzene 

Downstream Products

• 471903-41-0 trans-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanol 
• 471905-53-0 cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanol 
• 471903-69-2 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexyl]-acetic acid 
• 471903-67-0 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexyl]-acetic acid ethyl ester 
• 471903-70-5 C₂₄H₂₆ClF₂NO₄S 
• 471905-47-2 C₂₃H₂₅ClF₂O₄S 
• 471905-38-1 C₂₂H₂₃ClF₂N₂O₄S 
• 471903-20-5 4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanone 

Relevant academic research and scientific papers

3-Substituted gem-cyclohexane sulfone based γ-secretase inhibitors for Alzheimer's disease: Conformational analysis and biological activity

Previously, chemistry effort on the gem-cyclohexane series of γ-secretase inhibitors has focused on the 4-position of the cyclohexane ring. Recently chemistry has been directed towards the 3-position and substitution here has also provided compounds with

CYCLOHEXYL SULPHONES FOR TREATMENT OF CANCER

Sulphones of formula (I) are disclosed for use in treatment of cancer.

The new cyclohexylpropionic sulfone

Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.