471905-53-0Relevant articles and documents
CYCLOHEXYL SULPHONES FOR TREATMENT OF CANCER
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, (2010/11/25)
Sulphones of formula (I) are disclosed for use in treatment of cancer.
The conformational bias of aryl, arylsulfonyl geminally substituted tertiary carbon centers: Applications in substrate-based stereocontrol
Scott, Jeremy P.,Mullens, Peter R.,Brewer, Sarah E.,Brands, Karel M.J.,Chilenski, Jennifer R.,Davies, Antony J.,Gibb, Andrew D.,Lieberman, David R.,Oliver, Steven F.,Dolling, Ulf-H.
, p. 1806 - 1810 (2008/02/05)
Intramolecular nitrile oxide-olefin cycloaddition to form hexahydrobenzisoxazole 14, which engenders a phenylsulfonyl, 2,5-difluorophenyl geminally substituted carbon substructure, proceeds with up to 99% ds. A rationalization of the high level of substra
The new cyclohexylpropionic sulfone
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Page/Page column 14-15, (2008/06/13)
Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.