4744-10-9

Basic information

• Product Name: PROPIONALDEHYDE DIMETHYL ACETAL
• Synonyms: 3-Ethyl-2,4-dioxapentane;Propanal dimethyl acetal;PROPIONALDEHYDE DIMETHYL ACETAL;1,1-DIMETHOXYPROPANE;Propane, 1,1-dimethoxy-
• CAS NO: 4744-10-9
• Molecular Formula: C₅H₁₂O₂
• Molecular Weight: 104.15
• EINECS: 225-258-3
• Mol File: 4744-10-9.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 89°C
• Flash Point: 10°C
• Appearance: /
• Density: 0,85 g/cm3
• Vapor Pressure: 65.2mmHg at 25°C
• Refractive Index: 1.3780-1.3810
• CAS DataBase Reference: PROPIONALDEHYDE DIMETHYL ACETAL(CAS DataBase Reference)
• NIST Chemistry Reference: PROPIONALDEHYDE DIMETHYL ACETAL(4744-10-9)
• EPA Substance Registry System: PROPIONALDEHYDE DIMETHYL ACETAL(4744-10-9)

Safety Data

• Statements: 11
• Safety Statements: 26-36/37/39
• RIDADR: 1993
• HazardClass: 3.1
• PackingGroup: II
• Hazardous Substances Data: 4744-10-9(Hazardous Substances Data)

Usage

General Description

Propionaldehyde Dimethyl Acetal, also known as 2,2-Dimethoxypropane (CAS number 77-76-9), is a small organic compound of the molecular formula C5H12O2. It is most commonly used in the lab as a protecting group for aldehydes and ketones. It can undergo hydrolysis to form acetone and methanol, which is why it is also a stable precursor to acetone, used frequently in its transportation or storage. It may be synthesized from acetone through its reaction with methanol and a strong acid. This colorless liquid is considered flammable and should be used with appropriate precautions.

InChI:InChI=1/C5H12O2/c1-4-5(6-2)7-3/h5H,4H2,1-3H3

Upstream product

• 67-56-1 methanol 
• 108-03-2 1-Nitropropane 
• 301-00-8 methyl linolenate 
• 123-38-6 propionaldehyde 
• 149-73-5 trimethyl orthoformate 
• 116-11-0 2-Methoxypropene 
• 57-55-6 propylene glycol 
• 201230-82-2 carbon monoxide 
• 74-85-1 ethene 
• 107-18-6 allyl alcohol 
• 127248-84-4 1-ethoxy-1-methoxypropane 
• 4744-08-5 1,1-diethoxypropane 
• 64-17-5 ethanol 
• 681-84-5 tetramethylorthosilicate 

Downstream Products

• 33170-72-8 2-bromo-1,1-dimethoxypropane 
• 19967-57-8 bromo-2 propanal 
• 84952-69-2 2-methoxy-butyraldehyde 
• 802294-64-0 propionic acid 
• 10508-89-1 <1-Methoxy-propyl>-<α-phenyl-isopropyl>-peroxid 
• 1576-87-0 trans-2-pentenal 
• 111873-74-6 3-Methoxy-2-methyl-1-phenyl-pentan-1-one 
• 132786-08-4 (2R,6R)-2-Ethyl-4-ethylsulfanyl-5-methyl-6-phenyl-6H-[1,3]oxathiine 
• 547-64-8 2-Hydroxy-propionic acid methyl ester 
• 71-23-8 propan-1-ol 
• 64788-25-6 propoxycarbenium ion 
• 106-70-7 methyl hexanoate 
• 87894-32-4 2-chloropropionaldehyde dimethyl acetal 
• 67-56-1 methanol 

Relevant articles and documents

One-pot Synthesis of Acetals by Tandem Hydroformylation-acetalization of Olefins Using Heterogeneous Supported Catalysts

Abstract: A green route for one?pot synthesis of acetals by tandem hydroformylation?acetalization of olefins using supported Rh?based?catalysts was developed. Experimental results demonstrated that suitable Rh loading (1 wt%) with appropriate reaction temperature (120?°C) and reaction time (8?h) were favorable for the formation of acetals, and a high acetals selectivity of 94.6% was achieved. More importantly, the selectivity to valuable linear products was enhanced in this tandem catalysis. Based on the catalytic mechanism study, highly dispersed RhOx nanoparticles and abundant acid sites on the supports were responsible for the hydroformylation and acetalization, respectively. Graphical abstract: One-pot synthesis of acetals directly from olefins with high selectivity was achieved over heterogeneous bifunctional catalysts via tandem hydroformylation-acetalization. [Figure not available: see fulltext.]

METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL

Disclosed is a process for the reductive carbonylation of a low molecular weight alcohol to produce the homologous aldehyde and/or alcohol. The process includes conducting the reaction to produce the aldehyde in the presence of a single component catalyst complex composed of cobalt, an onium cation and iodide in a ratio of 1:2:4 without additional promoters. A ruthenium co-catalyst is used in the production of the homologous alcohol. The reductive carbonylation reaction does not require an additional iodide promoter and produces a crude reductive carbonylation product substantially free of methyl iodide.

PROCESSES FOR MAKING ACRYLIC-TYPE MONOMERS AND PRODUCTS MADE THEREFROM

Presently disclosed are processes for making acrylic acid and methacrylic acid along with their respective esters, from alkylene glycols such as ethylene glycol and propylene glycol. In particular, biobased acrylic acid and acrylic acid esters, methacrylic acid and methacrylic acid esters can be made starting with bioderived glycols from the hydrogenolysis of glycerol, sorbitol and the like.