474452-40-9Relevant academic research and scientific papers
First syntheses of two quinoline alkaloids from the medicinal herb Ruta chalepensis via cyclization of an o-iodoaniline with an acetylenic sulfone
Back, Thomas G.,Wulff, Jeremy E.
, p. 1710 - 1711 (2002)
The first syntheses of two quinoline alkaloids found in the medicinal herb Ruta chalepensis are reported via the conjugate addition of an o-iodoaniline to an acetylenic sulfone, followed by Pd-catalyzed carbonylation, intra-molecular acylation of the core
Conjugate additions of o-iodoanilines and methyl anthranilates to acetylenic sulfones. A new route to quinolones including first syntheses of two alkaloids from the medicinal herb Ruta chalepensis
Back, Thomas G.,Parvez, Masood,Wulff, Jeremy E.
, p. 2223 - 2233 (2007/10/03)
A novel synthesis of 2-substituted 4-quinolones was developed on the basis of the conjugate additions of appropriately ortho-substituted anilines to acetylenic sulfones followed by intramolecular acylation of the corresponding sulfone-stabilized anions. C
