4747-46-0

Usage

Uses

Used in Organic Synthesis:
1-phenyl-1H-pyrazole-3-carboxylic acid is used as a building block in organic synthesis for the creation of various complex organic molecules. Its unique structure allows for versatile chemical reactions, facilitating the synthesis of a wide range of compounds.
Used in Pharmaceutical Research:
1-phenyl-1H-pyrazole-3-carboxylic acid is utilized as a starting material in pharmaceutical research for the development of new drugs. Its potential biological activity and medicinal properties make it a promising candidate for the treatment of various conditions.
Used as an Enzyme Inhibitor:
In pharmaceutical research, 1-phenyl-1H-pyrazole-3-carboxylic acid is used as an enzyme inhibitor to modulate the activity of specific enzymes involved in disease processes. By inhibiting these enzymes, it may contribute to the development of therapeutic agents for treating related conditions.
Used as a Ligand for Metal Complexes:
1-phenyl-1H-pyrazole-3-carboxylic acid is employed as a ligand in the formation of metal complexes. Its ability to chelate metal ions can lead to the development of new materials with potential applications in various fields, including catalysis, sensing, and medicinal chemistry.
Used in Drug Development for Various Conditions:
1-phenyl-1H-pyrazole-3-carboxylic acid may have applications in the development of new drugs for the treatment of a range of conditions. Its potential biological activity and medicinal properties make it a valuable compound for exploring novel therapeutic approaches.

InChI:InChI=1/C10H8N2O2/c13-10(14)9-6-7-12(11-9)8-4-2-1-3-5-8/h1-7H,(H,13,14)

Upstream product

• 1128-54-7 3-methyl-1-phenyl-1H-pyrazole 
• 7188-95-6 methyl 1-phenyl-1H-pyrazole-3-carboxylate 
• 23429-68-7 1,1'-diphenyl-4,5,4',5'-tetrahydro-1H,1'H-[3,3']bipyrazolyl 
• 508191-77-3 3-phenylsydnone 
• 18093-85-1 1-phenyl-3-cyanopyrazole 
• 98-80-6 phenylboronic acid 
• 89-25-8 edaravone 
• 83959-41-5 1-phenyl-3-trichloromethyl-1H-pyrazole 
• 936-53-8 1-phenyl-4,5-dihydro-1H-pyrazole 
• 875440-31-6 2,2'-diphenyl-2H,2'H-5,5'-ethanediyl-bis-pyrazole-3-carboxylic acid diethyl ester 
• 100-63-0 phenylhydrazine 
• 107518-40-1 1-phenyl-1H-pyrazole-3,5-dicarboxylic acid 3-ethyl ester 

Downstream Products

• 7188-95-6 methyl 1-phenyl-1H-pyrazole-3-carboxylate 
• 509077-92-3 1-phenyl-1H-pyrazole-3-carboxylic acid hydrazide 
• 423768-37-0 1-phenyl-1H-pyrazole-5-carbonyl chloride 
• 458565-94-1 (1-phenyl-1H-pyrazol-3-yl)-carbamic acid ethyl ester 
• 458561-89-2 1-phenyl-1H-pyrazole-3-carbonyl azide 
• 2753-56-2 N-(1-phenyl-1H-pyrazol-3-yl)-acetamide 
• 1128-56-9 3-amino-1-phenylpyrazole 

Relevant academic research and scientific papers

Novel pyrazole derivatives via ring transformations: Anti-inflammatory and antifungal activity studies

In this paper, the synthesis of novel pyrazoles and their in vitro anti-inflammatory and in-vitro antifungal assay have been reported. These compounds were docked into the inducible nitric oxide synthase (iNOS) oxygenase dimer. The compounds 3c, 7a, 7c, 8

Photo-induced deep aerobic oxidation of alkyl aromatics

Oxidation is a major chemical process to produce oxygenated chemicals in both nature and the chemical industry. Presently, the industrial manufacture of benzoic acids and benzene polycarboxylic acids (BPCAs) is mainly based on the deep oxidation of polyalkyl benzene, which is somewhat suffering from environmental and economical disadvantage due to the formation of ozone-depleting MeBr and corrosion hazards of production equipment. In this report, photo-induced deep aerobic oxidation of (poly)alkyl benzene to benzene (poly)carboxylic acids was developed. CeCl3 was proved to be an efficient HAT (hydrogen atom transfer) catalyst in the presence of alcohol as both hydrogen and electron shuttle. Dioxygen (O2) was found as a sole terminal oxidant. In most cases, pure products were easily isolated by simple filtration, implying large-scale implementation advantages. The reaction provides an ideal protocol to produce valuable fine chemicals from naturally abundant petroleum feedstocks. [Figure not available: see fulltext.].

PYRAZOLE DERIVATIVES AS S1P1 AGONISTS

The present invention relates to a compound of formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by sphingosine-1-phosphate receptors (S1P1) agonists.

New pyrazole derivatives

The present invention relates to a compound of formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by sphingosine-1-phosphate receptors (S1P1) agonists.