4773-12-0

Basic information

• Product Name: Sulfurous acid diphenyl
• Synonyms: Sulfurous acid diphenyl;Sulfurous acid diphenyl ester
• CAS NO: 4773-12-0
• Molecular Formula: C₁₂H₁₀O₃S
• Molecular Weight: 234.27
• Mol File: 4773-12-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Sulfurous acid diphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: Sulfurous acid diphenyl(4773-12-0)
• EPA Substance Registry System: Sulfurous acid diphenyl(4773-12-0)

Safety Data

• Hazardous Substances Data: 4773-12-0(Hazardous Substances Data)

Upstream product

• 139-02-6 sodium phenoxide 
• 13165-73-6 phenyl chlorosulphinate 
• 108-95-2 phenol 
• 110-86-1 pyridine 
• 7719-09-7 thionyl chloride 
• 60-29-7 diethyl ether 
• 91-22-5 quinoline 
• 108-86-1 bromobenzene 
• 56-23-5 tetrachloromethane 
• 108-90-7 chlorobenzene 

Downstream Products

• 945-51-7 1,1'-sulfinylbisbenzene 
• 108-95-2 phenol 
• 5798-76-5 phenyl 4-bromobenzoate 
• 108-98-5 thiophenol 
• 115-86-6 phosphoric acid triphenyl ester 
• 17755-35-0 tris-(4-hydroxy-phenyl)-sulfonium ; chloride 
• 118-55-8 phenyl Salicylate 
• 621-08-9 Dibenzyl sulfoxide 
• 13165-73-6 phenyl chlorosulphinate 
• 33641-61-1 N,N,N′,N′-tetraethylthionylamide 
• 108-90-7 chlorobenzene 
• 1095-03-0 triphenylborane 
• 84511-86-4 phenyl 1-amidino-4-piperidineacetate hydrochloride 
• 84511-93-3 phenyl 1-amidino-3-piperidinepropionate hydrochloride 

Relevant articles and documents

A mild method for conversion of alcohols to dialkyl sulfites by use of Na2SO3/SOCl2

Alcohols are easily converted to their corresponding dialkyl sulfite under mild reaction conditions using Na2SO3/SOCl2 in moderate to good isolated yields.

Reactions of N-sulfinylfluoroalkanesulfonyl amines with nucleophiles containing reactive hydrogen

The reactions of N-sulfinylfluoroalkanesulfonyl amines, RfSO2NSO (1), with malonate or dialkyl phosphite gave 1:1 adducts RfSO2NHS(O)Nu , and with alcohols or phenols formed RfSO2NH2 and the sulfites O=S(OR)2 by double addition .Trans-sulfinylation occurred during the reaction of 1 with anilines (C6H5NH2, 4-FC6H4NH2 and C6F5NH2).

Conversion of Some Pyrimidine 2'-Deoxyribonucleosides into the Corresponding 2',3'-Didehydro-2',3'-dideoxynucleosides

Thymidine 4b was converted into 2,3'-anhydro-1-(2'-deoxy-β-D-threo-pentofuranosyl)thymine 7b in ca. 65percent isolated yield by being heated at 155 deg C with an excess of diphenyl sulfite and 1-methylimidazole in N,N-dimethylacetamide solution. 2'-Deoxyuridine 4a, 2'-deoxy-5-ethyluridine 4c and 2'-deoxy-5-fluorouridine 4d were similarly converted into 2,3'-anhydronucleosides which were isolated as their 5'-O-(tert-butyldimethylsilyl) derivatives 8a, 8c and 8d in 51, 50 and 59percent yield, respectively.When the oxetane derivatives 5a-d, prepared by the literature procedure from the parent 2'-deoxynucleosides 4a-d, were heated with an excess of sodium hydride in N,N-dimethylacetamide solution at 100 deg C, they were converted into the corresponding 2',3'-didehydro-2',3'-dideoxynucleosides 6a-d in 68, 76, 69 and 74percent isolated yield, respectively.The latter compounds were similarly prepared from the 2,3'-anhydronucleosides 7a-d in 71, 81, 69 and 74percent isolated yield, respectively. 2,3'-Anhydro-5'-O-(tert-butyldimethylsilyl)-2'-deoxy-5-(trifluoromethyl)- and -5-iodo-1-(β-D-threo-pentofuranosyl)uracil 8e and 8f, which were themselves prepared from the parent 2'-deoxynucleosides 4e and 4f, respectively, in ca. 60 and 50percent yield, were converted by a three-step procedure via the intermediate 2'-deoxy-3'-(phenylseleno) derivatives 10e and 10f into the corresponding 2',3'-didehydro-2',3'-dideoxynucleosides 6e and 6f in 52 and 49percent overall yield, respectively.Compound 8e was also converted into 2',3'-dideoxy-5-(trifluoromethyl)uridine 11b and 3'-azido-2',3'-dideoxy-5-(trifluoromethyl)uridine 11c in 49 and 66percent overall yield, respectively.