478519-02-7

Basic information

• Product Name: L-[1-13C]GLUCOSE
• Synonyms: L-[1-13C]GLUCOSE
• CAS NO: 478519-02-7
• Molecular Formula: C6H12O6
• Molecular Weight: 181.16
• Product Categories: Carbohydrates & Derivatives, Isotope Labelled Compounds
• Mol File: 478519-02-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-[1-13C]GLUCOSE(CAS DataBase Reference)
• NIST Chemistry Reference: L-[1-13C]GLUCOSE(478519-02-7)
• EPA Substance Registry System: L-[1-13C]GLUCOSE(478519-02-7)

Safety Data

• Hazardous Substances Data: 478519-02-7(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 478519-02-7 differently. You can refer to the following data:
1. L-[1-13C]Glucose is the enantiomer of D-Glucose (G595000), a naturally occurring carbohydrate used in an abundance of cellular processes. L-[1-13C]Glucose is a synthetic sugar used in the formation of L-Glucose Pentaacetate (G596510), a potential therapeutic agent regarding type II diabetes. In addition, L-[1-13C]Glucose can be used as a colon cleansing agent for before a colonoscopy procedure.
2. Labelled L-Glucose is the enantiomer of D-Glucose (G595000), a naturally occurring carbohydrate used in an abundance of cellular processes. L-Glucose is a synthetic sugar used in the formation of L-Glucose Pentaacetate (G596510), a potential therapeutic agent regarding type II diabetes. In addition, L-glucose can be used as a colon cleansing agent for before a colonoscopy procedure.

Upstream product

• 70849-16-0 D-<2-13C>glucose 
• 58-86-6 D-xylose 
• 213825-55-9 D-(1,5-13C₂)arabinose 
• 139657-61-7 D-(2,5-13C₂)ribose 
• 50-69-1 D-ribose 
• 1114-34-7 D-lyxose 
• 40010-55-7 <1-13C>-α-D-talopyranose 
• 40010-55-7 β-D-[1-13C]talopyranose 
• 10323-20-3 D-Arabinose 
• 40010-55-7 α- and β-D-<1-13C>mannose 
• 70849-31-9 <1-13C>-D-mannose 

Downstream Products

• 444313-77-3 C₁-¹³C-tri-O-benzyl-D-glucal 
• 287111-36-8 [U-(13)C6]-mevalonolactone 
• 1633-56-3 (¹³C)-formic acid 
• 478506-38-6 C₅⁽¹³⁾CH₁₂O₆ 
• 108311-21-3 <1-13C>-D-fructose 

Relevant articles and documents

STABILIZED ACYCLIC SACCHARIDE COMPOSITE AND METHOD FOR STABILIZING ACYCLIC SACCHARIDES AND APPLICATIONS THEREOF

Disclosed is a stabilized acyclic saccharide composite, which includes a LDH-based (layered double hydroxide-based) material and acyclic saccharides intercalated in interlayer regions of the LDH-based material. The acyclic saccharides stabilized and trapped in the LDH-based material give an opportunity for direct functionalization to other valuable molecules in the pharmaceutical, chemical or carbohydrate industries. Further, a novel pathway for saccharide transformation and aldol condensation without the drawbacks associated with enzymatic catalysts is achieved through the acyclic saccharides trapped by the LDH-based material.

Two-bond 13C-13C spin-coupling constants in carbohydrates: New measurements of coupling signs

D-(1,3,6-13C3)Allose (1), (13C)methyl α-D-(1,2-13C2)glucopyranoside (2) and (13C)methyl β-D-(1,2-13C2)glucopyranoside (3) were synthesized and used to establish the signs of their constituent 2J(CCC) or 2J(COC) values (2J(C1,C3) in the α-pyranose of 1 (15), and 2J(C1,CH3) in 2 and 3). Compounds 2, 3 and 15 contain three mutually coupled labeled carbons, thus creating a three-spin system from which crosspeak displacements in 13C-13C COSY-45 spectra were used to determine coupling signs. In all compounds, at least one 3J(CC) value was present as an internal reference: 3J(C2,CH3 in 2 and 3, and 3J(C1,C6) and 3J(C3,C6) in 15. 2J(C1,CH3), in 2 and 3, and 2J(C1,C3) in 15, were found to be negative, thus providing experimental confirmation of the sign predictions made via the projection resultant rule described recently.

HYDROXIDE-CATALYZED ISOMERIZATION OF D-(1-13C)MANNOSE: EVIDENCE FOR THE INVOLVEMENT OF 3,4-ENEDIOLS

The KOH-catalyzed isomerization of D-(1-13C)mannose under anaerobic conditions was studied by 13C-n.m.r. spectroscopy.D-(1-13C)Glucose and D-(1-13C)fructose are generated during the reaction, as expected.In addition, however, (6-13C)glucose, (6-13C)mannose, and (6-13C)fructose are produced in small proportions, possibly via symmetrical 3,4-enediol intermediates.The involvement of the latter structures in 13C-label shifting is inferred from the observation of (1-13C)sorbose and (6-13C)sorbose in the reaction mixture.