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1,1-Bis(p-methoxyphenyl)propane, also known as Butacaine or Benzocaine, is an organic compound with the chemical formula C19H22O2. It is a colorless, crystalline substance that is widely used as a local anesthetic in topical medications, such as creams and sprays, to relieve pain and itching caused by minor skin irritations, insect bites, and sunburns. The compound is derived from the combination of two p-methoxyphenyl groups attached to a propane chain, which contributes to its anesthetic properties. It is known for its rapid onset and short duration of action, making it a popular choice for temporary pain relief.

4792-39-6

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4792-39-6 Usage

Molecular weight

294.39 g/mol

Appearance

Colorless to white crystalline solid

Solubility

Soluble in organic solvents like ethanol, acetone, and diethyl ether

Melting point

108-111°C

Boiling point

Not available (decomposes before boiling)

Density

Not available (decomposes before boiling)

Production method

Derived from the reaction of acetone with two equivalents of phenol in the presence of an acid catalyst

Applications

Used in the production of epoxy resins and polycarbonate plastics

Consumer products

Found in food and beverage can linings, thermal paper, and electronics

Health concerns

Potential adverse health effects on the endocrine system

Environmental impact

Ongoing research and monitoring to understand its impact on human health and the environment

Safety and regulation

Concerns about its safety, leading to ongoing research and potential regulation changes

Chemical structure

Consists of a propane chain with two p-methoxyphenyl groups attached to the terminal carbons

Check Digit Verification of cas no

The CAS Registry Mumber 4792-39-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,9 and 2 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4792-39:
(6*4)+(5*7)+(4*9)+(3*2)+(2*3)+(1*9)=116
116 % 10 = 6
So 4792-39-6 is a valid CAS Registry Number.

4792-39-6Relevant academic research and scientific papers

Room-temperature bismuth-catalyzed bis-arylation of carbonyl compounds with aryl ethers and phenols

Liu, Congrong,Li, Manbo

, p. 1274 - 1278 (2013/11/06)

Using Bi2(SO4)3 as the catalyst and TMSCl as the additive, a wide variety of aldehydes, ketones, and acetals were smoothly condensed with aryl ethers at room temperature to provide the corresponding diarylmethanes and triarylmethanes selectively in good to excellent yields. Using Bi2(SO4)3 as the catalyst and TMSCl as the additive, a wide variety of aldehydes, ketones, and acetals were smoothly condensed with aryl ethers at room temperature to selectively provide the corresponding diarylmethanes and triarylmethanes in good to excellent yields. Copyright

Catalytic selective bis-arylation of imines with anisole, phenol, thioanisole and analogues

Liu, Cong-Rong,Li, Man-Bo,Yang, Cui-Feng,Tian, Shi-Kai

, p. 1249 - 1251 (2008/12/21)

The first highly efficient double Friedel-Crafts reaction of N-tosyl imines with anisole, phenol, thioanisole and analogues has been developed to produce the corresponding symmetric diarylmethanes and triarylmethanes with high regioselectivity in the presence of a catalytic amount of Bi2(SO 4)3-TMSCl at room temperature. The Royal Society of Chemistry.

Dual-reagent catalysis within Ir-Sn domain: Highly selective alkylation of arenes and heteroarenes with aromatic aldehydes

Podder, Susmita,Choudhury, Joyanta,Roy, Ujjal Kanti,Roy, Sujit

, p. 3100 - 3103 (2008/02/05)

(Chemical Equation Presented) Reactions of arenes and heteroarenes with aromatic aldehydes proceeded smoothly in the presence of a catalytic combination of [Ir(COD)Cl]2-SnCl4 to afford the corresponding triarylmethane derivatives (TRAMs) in high yields. This 100% TRAM selective transformation is clean and eliminates the use of acid systems.

Activation conditions play a key role in the activity of zeolite CaY: NMR and product studies of Bronsted acidity

Kao, Hsien-Ming,Grey, Clare P.,Pitchumani, Kasi,Lakshminarasimhan,Ramamurthy

, p. 5627 - 5638 (2007/10/03)

CaY, activated under different conditions, was characterized with 1H, 31P, and 1H/27A] double resonance MAS NMR. The 1H MAS NMR spectra of CaY, calcined in an oven at 500 °C, shows resonances from H2O (bound to Ca2+ and the zeolite framework), CaOH+, aluminum hydroxides, silanols, and Bronsted acid sites. No evidence for Lewis acidity is observed on adsorption of trimethylphosphine, and an estimate of ≈16 Bronsted acid sites per unit cell is obtained for this sample. CaY activated in an oven at higher temperatures contains less water, but all the other species are still present. In contrast, CaY activated by slow ramping of the temperature under vacuum to 500 or 600 °C shows a much lower concentration of Bronsted acid sites (1/unit cell). Again, no evidence for Lewis acidity was observed. These NMR results have been utilized to understand the very different product distributions that are observed for reactions of 1,1- and 1,2-diarylethylenes in zeolite CaY activated in an oven (in air) and under vacuum. Samples with high concentrations of Bronsted acid sites react stoichiometrically with these sites, yielding diarylalkanes. At low concentrations, the Bronsted acid sites can act catalytically resulting in isomerization reactions.

Molybdenum-catalyzed aromatic substitution with olefins and alcohols

Shimizu, Isao,Khien, Kuok Meng,Nagatomo, Miki,Nakajima, Takayuki,Yamamoto, Akio

, p. 851 - 852 (2007/10/03)

A new type of electrophilic aromatic substitution without using organic halides has been realized by using Mo(CO)6 catalyst.

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