4835-96-5

Basic information

• Product Name: L-MENTHYL ACRYLATE
• Synonyms: L-MENTHYL ACRYLATE
• CAS NO: 4835-96-5
• Molecular Formula: C₁₃H₂₂O₂
• Molecular Weight: 210.31
• Product Categories: monomer
• Mol File: 4835-96-5.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 111-112.5℃ (12 Torr)
• Flash Point: 102°C
• Appearance: /
• Density: 0.93g/cm³
• Vapor Pressure: 0.0132mmHg at 25°C
• Refractive Index: 1.4628 (589.3 nm 20℃)
• CAS DataBase Reference: L-MENTHYL ACRYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: L-MENTHYL ACRYLATE(4835-96-5)
• EPA Substance Registry System: L-MENTHYL ACRYLATE(4835-96-5)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 4835-96-5(Hazardous Substances Data)

Usage

General Description

L-Menthyl Acrylate is a chemical compound that belongs to the class of acrylate esters. It is derived from menthol, which is a natural compound found in peppermint oil. L-Menthyl Acrylate is commonly used in the production of adhesives, sealants, and coatings due to its ability to improve the flexibility and impact resistance of polymers. It is also utilized in the synthesis of polymers with enhanced properties such as adhesion, elongation, and impact resistance. Additionally, this chemical is known for its cooling properties, which makes it suitable for use in personal care and cosmetic products such as lip balms, moisturizers, and sunscreens. However, it is important to handle L-Menthyl Acrylate with caution as it can cause skin and eye irritation, and may be harmful if swallowed or inhaled.

InChI:InChI=1/C13H22O2/c1-5-13(14)15-12-8-10(4)6-7-11(12)9(2)3/h5,9-12H,1,6-8H2,2-4H3

Upstream product

• 2216-51-5 (-)-menthol 
• 814-68-6 acryloyl chloride 
• 15356-70-4 menthol 
• 86198-29-0 cyclohexanone oxime acrylate 
• 108-31-6 maleic anhydride 
• 89-78-1 menthol 
• 79-10-7 acrylic acid 
• 10458-14-7 (2R,5S)-menthone 
• 292638-85-8 acrylic acid methyl ester 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 128737-35-9 2-(Furan-2-yl-hydroxy-methyl)-acrylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 85238-74-0 3-Phenyl-2-p-tolyl-isoxazolidine-5-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 137441-55-5 C₃₁H₃₈N₂O₃ 
• 137441-51-1 C₂₄H₃₂N₂O₃ 
• 88536-95-2 (1S,2R)-2-Methyl-cyclohex-3-enecarboxylic acid (S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 123522-48-5 1-Methyl-5-oxo-bicyclo[2.2.2]octane-2-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 128797-16-0 (1S,4aS,8aR)-4-Oxo-decahydro-naphthalene-1-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 128797-16-0 (4aS,8aR)-4-Oxo-decahydro-naphthalene-1-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 85238-75-1 2-Benzyl-3-phenyl-isoxazolidine-5-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 85225-59-8 3-(4-Methoxy-phenyl)-2-phenyl-isoxazolidine-5-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 135457-93-1 (1S,5R,6S)-3-Benzyl-8-methyl-2,4-dioxo-3,8-diaza-bicyclo[3.2.1]octane-6-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 135457-93-1 (1S,5R,6R)-3-Benzyl-8-methyl-2,4-dioxo-3,8-diaza-bicyclo[3.2.1]octane-6-carboxylic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 114687-41-1 2-(Pyridin-2-ylsulfanyl)-pentanoic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 

Relevant articles and documents

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Stereoselective synthesis of novel C-3 functionalized 3-sulfonyl-β-lactams: Promising biologically active heterocyclic scaffolds

An efficient and operationally simple strategy for the stereoselective synthesis of novel C-3 functionalized 3-sulfonyl-β-lactam heterocycles is described. The C-3 functionalized 3-phenyl/benzylsulfonyl-β-lactams 3/3′, 5/5′ has been synthesized via Michael addition using different Michael acceptors on trans-3-phenyl/benzylsulfonyl-β-lactams 2(a–f) using K2CO3as a base and acetonitrile/DMF as solvents. The reaction furnished exclusively cis-β-lactam adducts 3(a–r) using sterically less hindered Michael acceptors. Further, the effect of steric bulk and chiralilty of Michael acceptors was explored to achieve target C-3 functionalized β-lactams 3(s-u)/3′(s-u) and 5(a–c)/5′(a–c). The structural and stereochemical analysis of novel β-lactams were carried out using FT-IR, NMR (1H,13C,1H-1H COSY,1H-13C COSY and13C DEPT-135), elemental analysis (CHNS), mass spectrometry (EIMS and LCMS) in representative cases and single crystal X-ray crystallographic studies (3e). The cis or trans configuration of the Michael acceptor (E) at C-3 was assigned with respect to C4-H.

Visible-Light-Induced Trifluoromethylation of Allylic Alcohols

An organic photoredox-catalyzed dehydroxylative trifluoromethylation of allylic alcohols was developed in an environmentally benign manner. In this reaction, the readily available CF3SO2Na was selected as the trifluoromethylation reagent. The in situ generated byproduct SO2 was reutilized to activate C-OH bond, which enabled this dehydroxylative trifluoromethylation to be performed conveniently. A variety of multifunctionalized CF3-allylic compounds were obtained in high yields and excellent stereoselectivity.

Late-Stage Macrocyclization of Bioactive Peptides with Internal Oxazole Motifs via Palladium-Catalyzed C-H Olefination

Oxazole is an important pharmacophore and exists in the backbone of many bioactive peptide natural products and peptidomimetics. Efficient methods for the synthesis and direct functionalization of complex oxazole-containing peptides are in high demand. Herein, we report the late-stage site-selective functionalization of oxazole-containing peptides via palladium-catalyzed δ-C(sp2)-H olefination of phenylalanine, tryptophan, and tyrosine residues. This strategy utilizes oxazole motifs as internal directing groups and provides access to oxazole-containing peptide macrocycles with bioactivities.