4855-68-9

Basic information

• Product Name: 2-Cyclohexyl-6-methylphenol
• Synonyms: 2-Cyclohexyl-6-methylphenol;6-Cyclohexyl-o-cresol
• CAS NO: 4855-68-9
• Molecular Formula: C₁₃H₁₈O
• Molecular Weight: 190.28
• Mol File: 4855-68-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 253.2°C at 760 mmHg
• Flash Point: 114.6°C
• Appearance: /
• Density: 1.026g/cm³
• Vapor Pressure: 0.0116mmHg at 25°C
• Refractive Index: 1.547
• CAS DataBase Reference: 2-Cyclohexyl-6-methylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexyl-6-methylphenol(4855-68-9)
• EPA Substance Registry System: 2-Cyclohexyl-6-methylphenol(4855-68-9)

Safety Data

• Hazardous Substances Data: 4855-68-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H18O/c1-10-6-5-9-12(13(10)14)11-7-3-2-4-8-11/h5-6,9,11,14H,2-4,7-8H2,1H3

Upstream product

• 542-18-7 cyclohexyl chloride 
• 95-48-7 ortho-cresol 
• 108-93-0 cyclohexanol 
• 7446-70-0 aluminium trichloride 
• 110-83-8 cyclohexene 
• 7637-07-2 boron trifluoride 
• 67698-81-1 1-(cyclohexyloxy)-2-methylbenzene 
• 108-94-1 cyclohexanone 
• 59334-09-7 2-Methyl-6-(cyclohexen-1-yl)-anisole 
• 15173-99-6 6-Cyclohexyl-o-tolyl methylaether 

Downstream Products

• 109276-59-7 methyl 3-(3-cyclohexyl-4-hydroxy-5-methylphenyl)propionate 
• 956479-65-5 butyl 3-(3-methyl-5-cyclohexyl-4-hydroxyphenyl)propyl sulfide 
• 956479-94-0 4-allyl-2-methyl-6-cyclohexylphenol 
• 956479-85-9 1-allyloxy-2-methyl-6-cyclohexylbenzene 
• 41468-67-1 2-cyclohexyl-4-dimethylaminomethyl-6-methyl-phenol 

Relevant articles and documents

Synthesis and antioxidant properties of sodium S-[3-(hydroxyaryl)propyl] thiosulfates and [3-(hydroxyaryl)propane]-1-sulfonates

Sodium S-[3-(hydroxyaryl)propyl] thiosulfates and [3-(hydroxyaryl)propane]- 1-sulfonates with various spatial hindrance of their phenolic OH groups were synthesized from dialkylphenols via a number of intermediate products. On a model reaction of oxidation of methyl oleate in aqueous sodium dodecyl sulfate, the rate constants of the interaction of the synthesized compounds with lipoperoxide radicals were determined.

Synthesis, Biological Evaluation, and Preliminary Structure-Activity Considerations of a Series of Alkylphenols as Intravenous Anesthetic Agents

Following our discovery of the intravenous (iv) anesthetic activity of 2,6-diethylphenol in mice, a series of alkylphenols was examined in this species and the most active analogues were further evaluated in rabbits.The synthesis of compounds which were not commercially available was accomplished by adaptations of standard ortho-alkylation procedures for phenols.Structure-activity relationships were found to be complex, but, in general, potency and kinetics appeared to be a function of both the lipophilic character and the degree of steric hindrance exerted by ortho substituents.The most interesting compounds were found in the 2,6-dialkyl series, and the greatest potency was associated with 2,6-di-sec-alkyl substitution.In particular, 2,6-diisopropylphenol (ICI 35868) emerged as a candidate for further development and has subsequently been shown to be an effective iv anesthetic agent in man.