489-39-4 Usage
Description
(+)-Aromadendrene, a sesquiterpenoid, is the major constituent of the essential oil of Eucalypfus globulus. It is an organic compound that belongs to the class of terpenes, which are a large and diverse group of naturally occurring hydrocarbons derived from plants.
Uses
Used in Pharmaceutical Industry:
(+)-Aromadendrene is used as a chiral starting material for the synthesis of other sesquiterpenes such as (-)-apoaromadendrone, (-)-kessane, (+)-spathulenol, (+)-ledene, and (-)-isoledene. These synthesized compounds have potential applications in the development of new drugs and pharmaceuticals due to their diverse chemical structures and biological activities.
Used in Fragrance Industry:
(+)-Aromadendrene, being a major constituent of the essential oil of Eucalypfus globulus, is used as a raw material in the fragrance industry. Its unique scent and properties make it a valuable component in the creation of various perfumes, colognes, and other scented products.
Used in Flavor Industry:
In addition to its use in the fragrance industry, (+)-Aromadendrene can also be utilized in the flavor industry. Its distinct taste and aroma can be incorporated into the development of various food and beverage products, enhancing their overall flavor profile.
Used in Cosmetic Industry:
The potential applications of (+)-Aromadendrene extend to the cosmetic industry as well. Its unique properties can be harnessed to create innovative skincare and beauty products, offering consumers new and improved experiences.
Check Digit Verification of cas no
The CAS Registry Mumber 489-39-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 9 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 489-39:
(5*4)+(4*8)+(3*9)+(2*3)+(1*9)=94
94 % 10 = 4
So 489-39-4 is a valid CAS Registry Number.
489-39-4Relevant articles and documents
Synthetic studies on aromadendrane-type compounds. III. Stereoselective total syntheses of (+)-aromadendrene and (-)-alloaromadendrene
Tanaka,Maeda,Mikamiyama,Funakoshi,Uenaka,Iwata
, p. 4257 - 4268 (1996)
The stereoselective total syntheses of (+)-aromadendrene (5) and (-)-alloaromadendrene (6) were achieved via (+)-(1S,2R,4R,7S,11R)-7-tert-butyldimethylsiloxymethyl-3,3,11-trimethy ltricyclo[6.3.0.02,4]undec-8-en-10-one (7) as a common intermediate.
The synthesis of mono- and dihydroxy aromadendrane sesquiterpenes, starting from natural (+)-aromadendrene-III
Gijsen, Harrie J. M.,Wijnberg, Joannes B. P. A.,Stork, Gerrit A.,De Groot, Aede,De Waard, Maarten A.,Van Nistelrooy, Johannes G. M.
, p. 2465 - 2476 (2007/10/02)
The monoalcohols (-)-globulol (2), (-)-epiglobulol (3), (-)-ledol (4), and (+)-viridiflorol (5) were synthesized from (+)-aromadendrene (1). The cis-fused alloaromandedrone (14), the key intermediate used in the synthesis of 4 and 5, was obtained from the trans-fused apoaromadendrone (13) via a selective protonation of the thermodynamic enol trimethylsilylether 15. After hydroxylation of the tertiary C11 of 13 with RuO4, (+)-spathulenol (6), (-)-allospathulenol (7), and the aromadendrane diols 8-11 could be prepared. Compounds 2-11 were tested for antifungal properties, but their activity was only moderate.