4916-40-9

Usage

Uses

Used in Organic Synthesis:
Pyridine, 2,2(1,2-ethanediyl)bisis used as a reagent in organic synthesis for its ability to facilitate various chemical reactions, contributing to the creation of a wide range of organic compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Pyridine, 2,2(1,2-ethanediyl)bisis used as a solvent for its capacity to dissolve a broad spectrum of substances, which is essential in the development and manufacturing of various medications.
Used in Agricultural Industry:
Pyridine, 2,2(1,2-ethanediyl)bisis also utilized in the agricultural sector as a solvent, playing a role in the formulation of agricultural chemicals that require specific solubility properties for effective application.
Used in the Production of Rubber Chemicals:
Pyridine, 2,2(1,2-ethanediyl)bisis employed in the production of rubber chemicals, where it contributes to the development of materials with specific properties required for various applications in the rubber industry.
Used in the Production of Dyes:
Pyridine, 2,2(1,2-ethanediyl)bisis used in the production of dyes, where its chemical structure aids in creating colorants with particular characteristics for use in different industries.
Precautionary Measures:
Given its potential to be irritating to the eyes, skin, and respiratory system, as well as its toxicity to aquatic organisms, care should be taken when handling Pyridine, 2,2(1,2-ethanediyl)bis-. It is important to implement proper safety measures and disposal methods to minimize its impact on the environment and human health.

Upstream product

• 100-69-6 2-vinylpyridine 
• 95-47-6 o-xylene 
• 110-82-7 cyclohexane 
• 106-42-3 para-xylene 
• 108-38-3 m-xylene 
• 108-88-3 toluene 
• 108-67-8 1,3,5-trimethyl-benzene 
• 109-06-8 α-picoline 
• 94-36-0 dibenzoyl peroxide 
• 1121-60-4 pyridine-2-carbaldehyde 
• 931-19-1 2-methylpyridine N-oxide 
• 67-56-1 methanol 
• 71-43-2 benzene 
• 1749-29-7 2-pyridylmethyllithium 

Downstream Products

• 13337-53-6 1,2-Bis-(pyridyl-2)-aethan-N,N'-dioxyd 
• 1445895-96-4 C₂₄H₂₂N₂Pt 
• 1445896-06-9 C₂₂H₂₅N₂OPt⁽¹⁺⁾*C₃₂H₁₂BF₂₄^(1-) 

Relevant academic research and scientific papers

Triazolopyridines. Part 30.1 Hydrogen transfer reactions; Pyridylcarbene formation

The transfer hydrogenation reaction of [1,2,3]triazolo[1,5-a]pyridines with Pd/C/Zn or Pd(OH)2/C/Zn in water, ethanol or water/ethanol mixture has been explored. 4,5,6,7-Tetrahydrotriazolopyridines were obtained in good to medium yields. In addition, under the same conditions 2-substituted pyridines were also formed as a result of intermediate pyridylcarbene formation, by triazole ring opening and loss of nitrogen.

REACTIVITY OF HETEROAROMATIC ALDEHYDES WITH LOW VALENT TITANIUM

Behaviour of various aromatic heterocycles under dicarbonylic coupling with low valent titanium was studied.The results showed that the electron donating properties of the ring affect the degree of oxidation of the coupled compound.

ELEMENTAL SULFUR REACTIONS WITH 2-PICOLINE

A study of the reaction of the elemental sulfur with 2-picoline is reported.The process was carried out at the boiling point of the 2-picoline under argon.After removing unreacted solids, the reaction products were identified by means of LC, GC and GC-MS.The following products have been identified by mass spectrometry: 1,2-di/2-pyridyl/-ethane, 1,2-di/2-pyridyl/-ethene, 2-methyl-x-pyridines, 2-mercapto-methyl--pyridines, 1-mercapto-1,2-di/2-pyridyl/-ethane, 5,6-di/2-pyridyl/-5H-cyclopenta-pyridine, 5,6-di/2-pyridyl/-7H-cyclopentapyridine, 1,2,3-tri/2-pyridyl/-propane, 1,2-di/2-pyridyl/-1--ethane, 5,6-di/2-pyridyl/-7--7H-cyclopentapyridine, 5,6-di/2-pyridyl/-5--5H-cyclopentapyridine, dipyridyl>> sulfide and dipyridyl>> disulfide.

HOMOLYTIC PYRIDYLETHYLATION OF CYCLOHEXANE AND TETRALIN

The homolytic pyridylethylation of cyclohexene and tetraline with 2-vinylpyridine under conditions of peroxide and thermal initiation was investigated.In addition to the main reaction products, i.e., cycloalkylethylpyridines (1 : 1 adducts), compounds indicating rearrangement of the radicals with H migration were also isolated and identified.

PH-Functional Phosphanes with 2-Pyridyl Substituents in α- or β-Position 2-C5H4N-n-PRH (R = H, iPr, tBu, Ph, 2-C5H4N-n; n = 1, 2)

PH-functional phosphanes containing a 2-pyridyl substituent in α- or β-position to phosphorus, e.g. 2-C5H4N-n-PRH (R = H, iPr, tBu, Ph; n = 1, 2) have been obtained.The reactivity of the PH-groups can be employed for the synthesis of tridentate NPN-hybrid donors, 2PR (R = H, Ph).The phosphanes 2-C5H4N-n-PRH behave as monodentate ligands in transition metal complexes and form labile chelate ring systems.They may bridge metal-metal bonds to form seven membered ring systems, e.g.Mo2PC3N.The coordination of the N-donor of the ligands 2-C5H4N- n-PRH to a transition metal atom is indicated by a lowfield shift and a small (31)P-(13)C-splitting of the 13C NMR signal of carbon atom 6 in the pyridin ring system. - 2-Pyridyl Substituent, Reactions at PH-Functions, Chelate Complexes, Ligand Replacement, 13C NMR Spectra

Excimer Emission in Protonated Pyridine Systems. 2. Excimer Emission of Protonated Dipyridylalkanes in Solution at Room Temperature and 77 K

Emission properties of (2-pyridyl)-(CH2)n-(2-pyridyl) (n = 2, 3, 5, and 7) and (4-pyridyl)-(CH2)n-(4-pyridyl) (n = 2, 3, and 5) were studied in solution in the presence of trifluoroacetic acid at room temperature and 77 K.At room temperature, only 1,3-di(2-pyridyl)propane exhibits a very weak fluorescence at approximately 6900 cm-1 to the red of the normal fluorescence.This band is ascribed to an intramolecular excimer fluorescence between the protonated pyridine moieties.However, 4,4'-dipyridylalkanes do not fluoresce.At 77 K, being specific to a mixed solvent of tetrahydrofuran, methanol, and methyltetrahydrofuran (4:3:1 by volume), the protonated 2,2'-dipyridylalkanes exhibit a structureless band around around 325 nm besides the normal fluorescence band, but they exhibit no excimer fluorescence.On the other hand, the protonated 4,4'-dipyridylalkanes apparently exhibit only a structureless band around 325 nm.The 325-nm fluorescence band comes from a dimerlike excimer in which the protonated pyridine moieties interact intermolecularly in the excited state.The efficiency of the dimerlike excimer formation is independent of the length of methylene chain.From studies on the effects of solvent and temperature on the dimerlike excimer emission, it is found that the formation of the dimerlike excimer is strongly related to a solvent cage effect.

FREE-RADICAL PYRIDYLETHYLATION OF ARYLALKANES

2-(3-Arylpropyl)pyridines were synthesized in 30-54percent yields by the free-radical addition of toluene, o-, m-, and p-xylenes, and mesitylene to 2-vinylpyridine at 250-350 deg C.The products of rearrangement of the intermediate adduct radical with 1,3-H migration were isolated and identified.

Flash Vacuum Pyrolysis of Substituted Pyridine N-Oxides and Its Application to Syntheses of Heterocyclic Compounds

Flash vacuum pyrolysis of 2-picoline N-oxide gave 2-picoline, pyridine, 2-ethylpyridine, 2-vinylpyridine, 2-pyridylmethanol, bis(2-pyridyl)methane, 1,2-bis(2-pyridyl)ethane, and 1,2-bis(2-pyridyl)ethylene.These reactions are explained by intermediary participation of the 2-picolyl radical.Flash vacuum pyrolysis of methyl-substituted 2-benzylpyridine N-oxides led to methyl-substituted pyridoindoles or to benzoquinoline in moderate yields.