4926-52-7

Basic information

• Product Name: Imidazo[1,2-a]pyridine,2-chloro-3-nitro-
• Synonyms: Imidazo[1,2-a]pyridine,2-chloro-3-nitro-;MPYABESQQVTTRX-UHFFFAOYSA-N
• CAS NO: 4926-52-7
• Molecular Formula: C₇H₄ClN₃O₂
• Molecular Weight: 197.57856
• Mol File: 4926-52-7.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Density: 1.66g/cm³
• Refractive Index: 1.724
• CAS DataBase Reference: Imidazo[1,2-a]pyridine,2-chloro-3-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[1,2-a]pyridine,2-chloro-3-nitro-(4926-52-7)
• EPA Substance Registry System: Imidazo[1,2-a]pyridine,2-chloro-3-nitro-(4926-52-7)

Safety Data

• Hazardous Substances Data: 4926-52-7(Hazardous Substances Data)

Usage

General Description

Imidazo[1,2-a]pyridine,2-chloro-3-nitro- is a chemical compound with the molecular formula C7H4ClN3O2. It is a nitro-substituted imidazo[1,2-a]pyridine derivative, which is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. Imidazo[1,2-a]pyridine,2-chloro-3-nitro- is known for its diverse range of biological activities, including as an antibacterial, antifungal, and antiviral agent. It is mainly used as an intermediate in the production of various drugs and chemicals, due to its versatile reactivity and structural features. Imidazo[1,2-a]pyridine,2-chloro-3-nitro- is an important compound in the field of medicinal and organic chemistry, and its potential applications make it a valuable and significant chemical in the industry.

InChI:InChI=1/C7H4ClN3O2/c8-6-7(11(12)13)10-4-2-1-3-5(10)9-6/h1-4H

Upstream product

• 504-29-0 2-aminopyridine 
• 3999-05-1 2-chloroimidazo[1,2-a]pyridine 
• 126202-06-0 2-(2-imino-1,2-dihydropyridin-1-yl)acetic acid 

Downstream Products

• 89717-74-8 1-methyl-3-nitroimidazo<1,2-a>pyridinium-2-anilide 
• 3999-29-9 2-phenylimidazo[1,2-a]pyridin-3-amine 
• 171628-63-0 1-Phenyl-3-(2-phenyl-imidazo[1,2-a]pyridin-3-yl)-urea 
• 1110272-22-4 N,2-diphenylimidazo[1,2-a]pyridin-3-amine 
• 1072106-67-2 C₁₉H₁₄N₄O₂ 
• 1452807-22-5 N-(4-chlorophenyl)-2-phenylimidazo[1,2-a]pyridin-3-amine 
• 1452807-23-6 2-phenyl-N-(pyridin-3-yl)imidazo[1,2-a]pyridin-3-amine 
• 82193-32-6 3-amino-2-cyanoimidazo[1,2-a]pyridine 
• 956077-87-5 2-(4-methoxyphenyl)-3-nitroimidazo[1,2-a]pyridine 
• 1452807-18-9 2-(4-fluorophenyl)-3-nitroimidazo[1,2-a]pyridine 
• 22244-94-6 3-nitro-2-(4'-nitrophenyl)imidazo[1,2-a]pyridine 
• 1452807-24-7 C₁₃H₁₀N₄O₂ 

Relevant articles and documents

Synthesis and antibacterial activity in?vitro of 2-benzylthioimidazo[1,2-a]pyridine derivatives against pathogenic bacterial

To explore the antibacterial activity, a set of new 2-thiobenzyl-3-nitro-imidazo[1,2-a]pyridine derivatives were synthesized (9a–h) and characterized by NMR 1H, 13C and high-resolution mass (HRMS). These compounds were obtained by interaction between the 3-nitro-imidazo[1,2-a]pyridine isothiouronium salt (7) with benzyl chloride or bromide (8) in the presence of sodium hydroxide (NaOH). Eight (9a–h) of them were evaluated in?vitro on the positive gram bacterium (S. aureus ATCC 29213) and two others negative gram bacteria (P. aeruginosa ATCC 27853 and P. aeruginosa 933 C/21) by methods diffusion in solid medium and liquid macrodilution. Five among the eight compounds (9a, 9d, 9h, 9f and 9g) showed significant antibacterial activity on P. aeruginosa ATCC 27853 and P. aeruginosa 933 C/21with MIC between 7.81 and 250 μg/mL. All compounds were inactive on S. aureus. The compounds 9a and 9g were more potent on the two strains of P. aeruginosa ATCC 27853.

Pyridino-imidazopyrrole compound and application thereof

The invention provides a pyridino-imidazopyrrole compound, and belongs to the technical field of organic electroluminescent functional materials. The structural general formula is shown as a formula (I) or a formula (II), wherein in the formula (I) or the formula (II), R1, R2 and R3 are independently selected from hydrogen, C6-C16 aryl, a nitrogen atom-containing electron donating group or a nitrogen atom-containing electron withdrawing group respectively, and at least one of R1, R2 and R3 is a nitrogen atom-containing electron donating group. The compound provided by the invention has relatively balanced carrier transport performance, relatively high triplet state energy level and relatively high glass-transition temperature, is not easy to crystallize, has good thermal stability and film-forming property, can be used as a main body material, a sensitizing material and a doping material to be applied to a light-emitting layer of an organic light-emitting device, and the luminous efficiency and the service life of the device are effectively improved. The structural general formula is shown as the formula (I) or the formula (II).

HETERO-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME

The present specification relates to a novel heterocyclic compound and an organic light-emitting device using the same. According to one embodiment of the present specification, provided is a compound in chemical formula 1. The compound of the present specification can be used as an organic matter layer material of an organic light-emitting device.COPYRIGHT KIPO 2016