49561-31-1Relevant academic research and scientific papers
Intramolecular arylation of benzimidazoles via Pd(II)/Cu(I) catalyzed cross-dehydrogenative coupling
Pereira, Kyle C.,Porter, Ashley L.,Deboef, Brenton
, p. 1729 - 1732 (2014/03/21)
Electron poor benzimidazole substrates were arylated via an intramolecular cross-dehydrogenative coupling (CDC) reaction. These CDC reactions were catalyzed by a Pd(II)/Cu(I) catalyst system, capable of producing moderate yields on a large library of substrates. The substrate scope consisted of tethered arene-benzimidazoles that upon coupling, produced a fused polycyclic motif.
An efficient and convenient Cu(OAc)2/air mediated oxidative coupling of azoles via C-H activation
Li, Yan,Jin, Jun,Qian, Weixing,Bao, Weiliang
supporting information; experimental part, p. 326 - 330 (2010/02/16)
An efficient and convenient approach to construct C-C bonds at the 2-position of azoles via Cu(OAc)2/air mediated oxidative homo- and cross-coupling reaction was reported. The corresponding products were obtained in good to excellent yield.
Oxidative dimerization of azoles via copper(II)/silver(I)-catalyzed CH homocoupling
Monguchi, Daiki,Yamamura, Akira,Fujiwara, Taiki,Somete, Takashi,Mori, Atsunori
experimental part, p. 850 - 852 (2010/03/24)
When several azole derivatives such as imidazole, thiazole, and oxazole are treated with a catalyst system of copper(II)/silver(I) under oxygen atmosphere, oxidative dimerization at the CH bond of the 2-position takes place to afford the corresponding bisazoles up to 86% yield.
Synthesis and structures of 1,3,1′,3′-tetrabenzyl-2,2′-biimidazolidinylidenes (electron-rich alkenes), their aminal intermediates and their degradation products
Cetinkaya, Bekir,Cetinkaya, Engin,Chamizo, Jose A.,Hitchcock, Peter B.,Jasim, Hatam A.,Kuecuekbay, Hasan,Lappert, Michael F.
, p. 2047 - 2054 (2007/10/03)
Benzyl (R) substituted enetetramines 9 and 3 have been studied. From HNR(CH2)2NRH and CH(NMe)2OBut or CH(OMe)2NMe2, two new intermediates along the pathway to 9, namely the orthoamide 11 an
Synthesis and antimicrobial activity of substituted benzimidazole, benzothiazole and imidazole derivatives
Kucukbay,Cetinkaya,Durmaz
, p. 1331 - 1334 (2007/10/02)
New benzimidazole, benzothiazole and imidazole derivatives were synthesized by reacting electron-rich olefins (5, 23 and 29) with appropriate reagents. The compounds synthesized were identified by 1H, 13C-NMR, FT-IR and mass spectros
