49639-03-4

Basic information

• Product Name: (cyclohex-1-enyl)methyl phenyl sulfone
• Synonyms: (cyclohex-1-enyl)methyl phenyl sulfone
• CAS NO: 49639-03-4
• Molecular Weight: 236.335
• Mol File: 49639-03-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (cyclohex-1-enyl)methyl phenyl sulfone(CAS DataBase Reference)
• NIST Chemistry Reference: (cyclohex-1-enyl)methyl phenyl sulfone(49639-03-4)
• EPA Substance Registry System: (cyclohex-1-enyl)methyl phenyl sulfone(49639-03-4)

Safety Data

• Hazardous Substances Data: 49639-03-4(Hazardous Substances Data)

Upstream product

• 3112-85-4 methylphenylsulfonate 
• 23975-27-1 1-[(phenylsulfinyl)methyl]cyclohexanol 
• 1193-82-4 racemic methyl phenyl sulfoxide 
• 13307-75-0 (phenylthio)methyllithium 
• 108-94-1 cyclohexanone 
• 58960-47-7 Ethyl-γ,γ-pentamethylen-α-hydroxyaconat 
• 98-09-9 benzenesulfonyl chloride 
• 167389-29-9 (S)-N-methyl-S-(1-cyclohexen-1-ylmethyl)-S-phenylsulfoximine 
• 49639-02-3 (1-Chloro-cyclohexylmethanesulfonyl)-benzene 
• 96921-49-2 1-exo-methylenecyclohex-2-yl(phenyl) sulfone 
• 5330-61-0 1-nitromethyl-cyclohexene 
• 25932-11-0 benzenesulfinic acid sodium dihydrate 
• 873-55-2 sodium benzenesulfonate 
• 59807-87-3 1-(Benzolsulfonylmethyl)cyclohexanol 

Downstream Products

• 73114-08-6 2-Benzenesulfonyl-2-cyclohex-1-enyl-1-phenyl-ethanol 
• 68470-83-7 2-Benzenesulfonyl-1,2-di-cyclohex-1-enyl-ethanol 
• 100229-88-7 1-(cyclohexen-1-yl)-1-(phenylsulfonyl)ethane 
• 68826-56-2 Acetic acid (1S,2R)-2-benzenesulfonyl-1,2-di-cyclohex-1-enyl-ethyl ester 
• 68826-56-2 Acetic acid (1R,2R)-2-benzenesulfonyl-1,2-di-cyclohex-1-enyl-ethyl ester 
• 68826-53-9 (E)-(2-(cyclohex-1-en-1-yl)vinyl)benzene 

Relevant articles and documents

A method for the conversion of sulfoximines to sulfones: Application to polymer-bound sulfoximines and to the synthesis of chiral sulfones

Reaction of N-alkyl, N-aryl, and N-H sulfoximines with m- chloroperbenzoic acid cleanly gives the corresponding sulfones in high yield. In the case of the cleavage of N-alkyl and N-arylsulfoximines, formation of the corresponding nitroso compounds as the other reaction product was proven. Starting from enantio- and diastereopure sulfoximines, a number of chiral sulfones, including the axially chiral sulfone 6 and the sulfonyl- functionalized homoallylic alcohol 8, have been prepared. Reaction of the enantiopure sulfoximine 30 with Merrifield resin gave the polymer-bound sulfoximine 32. Oxidative cleavage of 32 afforded the sulfone 16 in high yield. Deprotonation of the sulfoximine resin 32 and reaction of Li-32 with benzaldehyde and propanal furnished the β-hydroxysulfoximine resins 33a and 33b, respectively. Oxidative cleavage of 33a and 33b readily afforded the β- hydroxy sulfones 14a and 14b, respectively.

Regioselective Preparation of Allylic Sulfones by Palladium-Catalyzed Reactions of Allylic Nitro Compounds with Sodium Benzenesulfinate

Treatment of allylic nitro compounds with sodium benzenesulfinate in the presence of 5 molpercent of Pd(PPh3)4 in N,N-dimethylformamide (DMF) at 20-70 deg C for 1-10 h resulted in the formation of allylic sulfones with predominance of kinetically controll

Chemo-, Regio-, and Diastereoselective Alkylation via Lewis Acid Promoted Substitutions of Sulfones

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