49790-83-2

Basic information

• Product Name: Glycine, N-phenyl-N-(phenylmethyl)-, ethylester
• Synonyms: Glycine, N-phenyl-N-(phenylmethyl)-, ethylester
• CAS NO: 49790-83-2
• Molecular Formula: C₁₇H₁₉NO₂
• Molecular Weight: 269.34
• Mol File: 49790-83-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Glycine, N-phenyl-N-(phenylmethyl)-, ethylester(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N-phenyl-N-(phenylmethyl)-, ethylester(49790-83-2)
• EPA Substance Registry System: Glycine, N-phenyl-N-(phenylmethyl)-, ethylester(49790-83-2)

Safety Data

• Hazardous Substances Data: 49790-83-2(Hazardous Substances Data)

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 758640-21-0 N-Benzylaniline 
• 62-53-3 aniline 
• 2216-92-4 N-phenylglycine ethyl ester 
• 100-39-0 benzyl bromide 
• 105-36-2 ethyl bromoacetate 
• 100-44-7 benzyl chloride 

Downstream Products

• 2216-92-4 N-phenylglycine ethyl ester 
• 107536-34-5 ethyl dipheny phenylalaninate 

Relevant articles and documents

Photoredox-Catalyzed α-Aminomethyl Carboxylation of Styrenes with Sodium Glycinates: Synthesis of γ-Amino Acids and γ-Lactams

A visible-light photoredox-catalyzed reductive α-aminomethyl carboxylation of styrenes with sodium glycinates and CO2 has been developed to synthesize a series of α,α-disubstituted γ-amino acids and γ-lactams with high efficiency and regioselectivity. Notably, CO2 released from the decarboxylation step can be reused for the subsequent carboxylation. Distinct from the previous reactions with the same type of substrates leading to simple decarboxylation and olefin hydroalkylation, this process involves additional CO2 sequestration, thus leading to olefin α-aminomethyl carboxylation. These findings not only provide new access to α,α-disubstituted γ-amino acids and γ-lactams but also serve as a proof of concept for CO2 reutilization in decarboxylation reactions.

AROMATIC COMPOUND

Provided is a novel aromatic ring compound having a GPR40 agonist activity and a GLP-1 secretagogue action. A compound represented by the formula: wherein each symbol is as described in the DESCRIPTION, or a salt thereof has a GPR40 agonist activity and a GLP-1 secretagogue action, is useful for the prophylaxis or treatment of cancer, obesity, diabetes, hypertension, hyperlipidemia, cardiac failure, diabetic complications, metabolic syndrome, sarcopenia and the like, and affords superior efficacy.