499194-65-9Relevant academic research and scientific papers
A convenient method for the synthesis of 4,4-diarylbut-1-enes via the successive allylation of aromatic aldehydes and the Friedel-Crafts alkylation reaction of aromatic nucleophiles with the intermediary benzyl silyl ethers using HfCl4 or Cl2Si(OTf)2
Shiina, Isamu,Suzuki, Masahiko,Yokoyama, Kazutoshi
, p. 6395 - 6398 (2002)
The three-component coupling reaction among aromatic aldehydes, allyltrimethylsilane and aromatic nucleophiles is efficiently performed by the promotion of HfCl4. A similar reaction occurs using allyltributyltin as the first nucleophile to aromatic aldehydes with a catalytic amount of Cl2Si(OTf)2 generated in situ from SiCl4 and AgOTf.
Palladium catalyzed isomerization of alkenes: A pronounced influence of an o-phenol hydroxyl group
Fan, Jinmin,Wan, Changfeng,Wang, Qiang,Gao, Linfeng,Zheng, Xiaoqi,Wang, Zhiyong
supporting information; experimental part, p. 3168 - 3172 (2011/02/25)
A novel palladium catalyzed isomerization of alkenes has been found, where an ortho-phenol hydroxyl group has a pronounced influence on the isomerization.
Secondary benzylation with benzyl alcohols catalyzed by a high-valent heterobimetallic Ir-Sn complex
Podder, Susmita,Choudhury, Joyanta,Roy, Sujit
, p. 3129 - 3132 (2008/02/07)
(Chemical Equation Presented) A highly efficient secondary benzylation procedure has been demonstrated using a high-valent heterobimetallic complex [Ir2(COD)2(SnCls)2(Cl)2(μ-Cl) 2] 1 as the catalyst in 1,2-dichloroethane to afford the corresponding benzylated products in moderate to excellent yields. The reaction was performed not only with carbon nucleophiles (arenes and heteroarenes) but also with oxygen (alcohol), nitrogen (amide and sulfonamide), and sulfur (thiol) nucleophiles. Mechanistic investigation showed the intermediacy of the ether in this reaction. An electrophilic mechanism is proposed from Hammett correlation.
