4994-16-5

Basic information

• Product Name: 4-PHENYL-1-CYCLOHEXENE
• Synonyms: (R,S)-Cyclohex-3-enyl-benzene;3-cyclohexen-1-yl-benzen;R,S-Cyclohex-3-enyl-benzene;4-PHENYLCYCLOHEXENE;4-PHENYL-1-CYCLOHEXENE;3-CYCLOHEXEN-1-YLBENZENE;4-phenylcyclohexen;(3-Cyclohexenyl)benzene
• CAS NO: 4994-16-5
• Molecular Formula: C₁₂H₁₄
• Molecular Weight: 158.24
• Mol File: 4994-16-5.mol
• Article Data: 24

Chemical Properties

• Melting Point: -14 °C
• Boiling Point: 235 °C
• Flash Point: -14 °C
• Appearance: colourless liquid
• Density: 0,97 g/cm3
• Vapor Pressure: 0.105mmHg at 25°C
• Refractive Index: n20/D1.539-1.545
• Storage Temp.: 2-8°C
• Solubility: Chloroform, Methanol (Slightly)
• Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
• BRN: 1930089
• CAS DataBase Reference: 4-PHENYL-1-CYCLOHEXENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PHENYL-1-CYCLOHEXENE(4994-16-5)
• EPA Substance Registry System: 4-PHENYL-1-CYCLOHEXENE(4994-16-5)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39
• RTECS: CZ1301000
• Hazardous Substances Data: 4994-16-5(Hazardous Substances Data)

Usage

Chemical Properties

colourless liquid

Uses

4-?Phenyl-?1-?cyclohexene is a volatile organic compound which may display the biological ability to reduce renal oxidative stress.

InChI:InChI=1/C12H14/c1-3-7-11(8-4-1)12-9-5-2-6-10-12/h1-5,7-8,12H,6,9-10H2

Upstream product

• 100-42-5 styrene 
• 590-19-2 2,3-dimethylbutene 
• 114895-10-2 phenylazoxy phenyl sulphone 
• 110-83-8 cyclohexene 
• 144121-60-8 1-phenylhex-5-en-1-ol 
• 5437-46-7 trans-4-phenylcyclohexanol 
• 23923-62-8 cis e trans-4-fenilacetilcicloesano 
• 64422-95-3 cis-4-Phenylcyclohexanolmethylether 
• 64422-96-4 trans-(4-methoxycyclohexyl)benzene 
• 170800-47-2 C₁₄H₂₀O 
• 17763-67-6 Phenyl triflate 
• 108-86-1 bromobenzene 
• 98-80-6 phenylboronic acid 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 

Downstream Products

• 56709-94-5 N-phenyl-2-phenyl-3-[(phenylamino)methylene]-1-cyclohexene-1-methanimine hydrochloride 
• 92-52-4 biphenyl 
• 56376-63-7 3-phenyl-adipic acid 
• 38671-80-6 4-phenyl-1,2-cyclohexanediol 

Relevant articles and documents

Olefination via Cu-Mediated Dehydroacylation of Unstrained Ketones

The dehydroacylation of ketones to olefins is realized under mild conditions, which exhibits a unique reaction pathway involving aromatization-driven C-C cleavage to remove the acyl moiety, followed by Cu-mediated oxidative elimination to form an alkene between the α and β carbons. The newly adopted N′-methylpicolinohydrazonamide (MPHA) reagent is key to enable efficient cleavage of ketone C-C bonds at room temperature. Diverse alkyl- and aryl-substituted olefins, dienes, and special alkenes are generated with broad functional group tolerance. Strategic applications of this method are also demonstrated.

Mechanistic insights into Br?nsted acid-induced nucleophilic substitution of aliphatic imidazole carbamate with halide ions

Herein we report interesting reactivity of imidazole carbamate towards nucleophilic substitution with halide ions under Br?nsted acidic conditions. Depending upon reaction conditions, halide ions could readily attack the carboxyl position and trigger decarboxylative alkyl halide formation. Alternatively, halide ions were also found to competitively undergo nucleophilic acyl substitution, which ultimately results in the generation of carbonate dimerization product.

Achieving vinylic selectivity in Mizoroki-heck reaction of cyclic olefins

In Heck reactions of cyclic olefins, the products usually have aryl groups that end up at the allylic and/or homoallylic position. We herein report new selectivity that adds aryl groups to the vinylic position. Cyclic olefins of various ring size worked well. The desired isomers were produced by palladium-hydride-catalyzed isomerization of the initial products. Thus, a specific catalyst must be used so that it can perform two jobs under one set of reaction conditions. Copyright