500719-87-9Relevant academic research and scientific papers
Preparation of 4-trifluoroethylidene-1,3-dioxolane derivatives via new stable (trifluoromethyl)ethynylation reagent
Jeong, In Howa,Jeon, Sung Lan,Kim, Bum Tae
, p. 7213 - 7216 (2003)
Perfluoroalkylated 4-trifluoroethylidene-1,3-dioxolane derivatives 2a-q were prepared in excellent yields from the reaction of new stable (trifluoromethyl)ethynylation reagent 1a with 1.3 equiv. of TBAF at -15°C for 10 min, followed by treatment with 2 equiv. of phenyl perfluoroalkylated ketone derivatives at room temperature. The reaction of 1a with 1.3 equiv. of TBAF, followed by treatment with 1 equiv. of aldehyde or ketone at -15°C for 10 min and then with trifluoroacetophenone (1 equiv.) at room temperature afforded perfluoroalkylated 4-trifluoroethylidene-1,3-dioxolane derivatives 2t-u in moderate yields.
Novel and efficient approach to (Z)-4-trifluoroethylidene-1,3-dioxolane derivatives via (trifluoromethyl)ethynylation of ketones and aldehydes
Jeon, Sung Lan,Choi, Ji Hoon,Cho, Jung Ah,Kim, Bum Tae,Jeong, In Howa
experimental part, p. 1018 - 1028 (2009/04/04)
Perfluoroalkylated 4-trifluoroethylidene-1,3-dioxolanes 2a-p were prepared in quantitative yields from the reaction of new stable (trifluoromethyl)ethynylation reagent 1a with TBAF at -15 °C for 10 min, followed by treatment with phenyl perfluoroalkylated
New approaches to β-trifluoromethylated enone derivatives
Jeong, In Howa,Jeon, Sung Lan,Kim, Myong Sang,Kim, Bum Tae
, p. 1629 - 1638 (2007/10/03)
β-Trifluoromethylated enaminones 1 were prepared stereospecifically or high stercoselectively in 31-92% yields from the reaction of Weinreb amides with trifluoropropynyl lithium, followed by quenching with H2O in the presence of amine derivativ
A novel approach to β-trifluoromethyl enaminones
Jeong, In Howa,Jeon, Sung Lan,Min, Yong Ki,Kim, Bum Tae
, p. 7171 - 7174 (2007/10/03)
β-Trifluoromethyl enaminones 1 were prepared in good yields from the reaction of trifluoropropynyl lithium with N-methoxy-N-methylbenzamide, followed by quenching with H2O in the presence of a variety of amines. The use of hydrazine or benzamid
