5016-08-0

Usage

Uses

Used in Pharmaceutical Applications:
2,3-diphenyl-1,2-dihydroquinoxaline is used as a neuroprotective agent for its potential role in the treatment of neurodegenerative diseases. It has demonstrated the ability to protect neurons from damage and degeneration, making it a promising candidate for therapeutic interventions in conditions such as Alzheimer's, Parkinson's, and other related disorders.
Used in Cancer Treatment Research:
In the field of oncology, 2,3-diphenyl-1,2-dihydroquinoxaline is used as a DNA repair inhibitor, which could potentially enhance the effectiveness of certain cancer treatments by preventing the repair of DNA damage caused by chemotherapy or radiation therapy. This application is still in the research phase, but it holds promise for improving cancer treatment outcomes.
Used in Antimicrobial Applications:
2,3-diphenyl-1,2-dihydroquinoxaline is used as an antimicrobial agent due to its ability to inhibit the growth of various microorganisms. This property makes it a candidate for development as a new class of antimicrobial drugs, which could be particularly useful in the context of increasing antibiotic resistance.
Used in Anti-Inflammatory Applications:
In the realm of inflammation management, 2,3-diphenyl-1,2-dihydroquinoxaline is used as an anti-inflammatory agent. Its potential to reduce inflammation could make it a valuable tool in the treatment of various inflammatory conditions, such as arthritis, asthma, and other autoimmune diseases.

Upstream product

• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 95-54-5 1,2-diamino-benzene 
• 7647-01-0 hydrogenchloride 
• 1684-14-6 2,3-diphenylquinoxaline 
• 134-81-6 benzil 

Downstream Products

• 1123652-62-9 1-acetyl-2,3-diphenyl-1,2-dihydro-quinoxaline 
• 1684-14-6 2,3-diphenylquinoxaline 
• 1123652-64-1 6,7-dibromo-2,3-diphenyl-quinoxaline 
• 7739-06-2 trans-1,2,3,4-tetrahydro-2,3-diphenylquinoxaline 
• 7739-06-2 cis-1,2,3,4-tetrahydro-2,3-diphenylquinoxaline 

Relevant academic research and scientific papers

Synthesis, physicochemical and optical characterization of novel fluorescing complex: O-phenylenediamine-benzoin

The complex of o-phenylenediamine (o-PDA) and benzoin (BN) was synthesized adopting solid state reaction by mixing of their melt together followed by chilling. The phase diagram study shows the formation of a complex in 1:1 molar ratio with congruent melt

Nano-BF3·SiO2: A reusable and eco-friendly catalyst for synthesis of quinoxalines

2,3-Disubstituted quinoxalines were synthesized via condensation of α-diketones and 1,2-phenylenediamines. Nano-BF3·SiO 2 as a "green" and reusable solid acid was used as the catalyst for the synthesis of quinoxalines. The reaction was carried out at room temperature under sonication with high to excellent yields.

Synthesis and investigation of mass spectra of some nitrogen heterocycles

2,3-DIPHENYL-1, 2-dihydro-quinoxaline (2), 2, 3-diphenyl-quinoxaline (3) and 2, 3-diphenyl-1, 2, 3, 4-tetrahydroquinoxaline (4) were prepared via the reaction of benzoin with o-phenylene diamine under different reaction conditions. Acylation of 2 and 4 with acetic anhydride yielded the corresponding N-acetyl (5) and N, N-1, 4-diacetyl derivative (7), respectively. Bromination of 2 with bromine gave the corresponding 6, 7-dibromo-2,3- diphenyl-quinoxaline (6). 2, 3, 5, 6-tetraphenylpyrazine (8) and 1-(benzylidene) amino-4, 5-diphenyl-1,5-dihydro-imidazoldine-2-thione (9) were synthesized by treatment of benzoin (1) with thiourea and benzaldehyde-thiosemicarbazone. The electron impact mass spectra of both of the above series of compounds have also been recorded and their fragmentation pattern is discussed.

The synthesis of quinoxalines by condensation reaction of acyleins with o-phenylenediamine without solvent under microwave irradiation

A convenient synthetic method for 2,3-disubstituted quinoxalines is described. Heating the aryl or alkyl acyloins and o-phenylenediamine in a microwave oven for 3-6 minutes affords 2,3-disubstituted quinoxalines in 20-94% yields.

Titanium(III) Chloride and Electrochemical Reduction of Pyrazine, Quinoxaline and Triazine Derivatives and of their Salts

The reduction of pyrazine, quinoxaline and triazine derivatives by titanium(III) chloride leads to di- or tetrahydrogenated compounds.High yields of tetrahydro compounds are also obtained through the reduction of quinoxalinium salts.These results are comp