503624-63-3

Basic information

• Product Name: 1-Naphthalenol, 1,2-dihydro-2-methyl-, (1R,2R)- (9CI)
• Synonyms: 1-Naphthalenol, 1,2-dihydro-2-methyl-, (1R,2R)- (9CI)
• CAS NO: 503624-63-3
• Molecular Formula: C11H12O
• Molecular Weight: 160.21238
• Product Categories: ALCOHOL
• Mol File: 503624-63-3.mol
• Article Data: 30

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Naphthalenol, 1,2-dihydro-2-methyl-, (1R,2R)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Naphthalenol, 1,2-dihydro-2-methyl-, (1R,2R)- (9CI)(503624-63-3)
• EPA Substance Registry System: 1-Naphthalenol, 1,2-dihydro-2-methyl-, (1R,2R)- (9CI)(503624-63-3)

Safety Data

• Hazardous Substances Data: 503624-63-3(Hazardous Substances Data)

Upstream product

• 573-57-9 1,4-dihydronaphthalene-1,4-epoxide 
• 75-24-1 trimethylaluminum 
• 118-92-3 anthranilic acid 
• 24825-00-1 naphthalene 1,2-oxide 
• 917-54-4 methyllithium 
• 14281-94-8 lithium tetramethyl alanate 
• 75-16-1 methylmagnesium bromide 
• 544-97-8 dimethyl zinc(II) 
• 557-20-0 diethylzinc 
• 13197-81-4 dimethyl(phenyl)aluminum 
• 6630-33-7 ortho-bromobenzaldehyde 
• 28272-96-0 2-vinylbenzaldehyde 
• 69611-02-5 (E)-2-(but-2-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 69611-01-4 (Z)-2-(but-2-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Relevant articles and documents

Palladium-catalyzed enantioselective ring opening of oxabicyclic alkenes with organozinc halides

Palladium-catalyzed asymmetric ring opening of oxabenzonorbornadienes with readily available organozinc halides under mild conditions in the presence of (S)-Pri-PHOX produces the corresponding 1,2-dihydronaphth-1-ols in good yield and high enan

Palladium-catalyzed enantioselective alkylative ring opening [2]

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Multinuclear Pd/Zn complex-catalyzed asymmetric alkylative ring-opening reaction of oxabicyclic alkenes

A multinuclear palladium catalyst can be used to realize the efficient catalytic asymmetric alkylative ring-opening reaction of oxabicyclic alkenes using dimethylzinc. The use of (R)-BINOL-PHOS bearing bisphosphine and diol moieties is essential for achieving excellent catalytic performance; the corresponding monophosphine and hydroxy-protected derivatives showed lower catalytic activities and/or enantioselectivities. The generation of Pd/Zn-multinuclear complexes is a key feature of the present catalysis.(Figure Presented)

Synthesis method of chiral compound of hydrogenated naphthalene structure unit

The invention discloses a synthesis method of a chiral compound of a hydrogenated naphthalene structure unit. In a methylbenzene/water solvent system, under the existence of catalysts of palladium acetate and R-(+)-1,1'-dinaphthalene-2,2'-diphenylphosphane, potassium trifluoroborate derivatives and oxa-benzo norbornene react at the room temperature to obtain the chiral compound of the hydrogenatednaphthalene structure unit through synthesis. The method provided by the invention has the advantages that the raw materials are cheap and can be easily obtained; the reaction conditions are mild; the post treatment is simple; the obtained target product yield and ee value are high.

Platinum-catalyzed anti-stereocontrolled ring-opening of oxabicyclic alkenes with Grignard reagents

A new platinum-catalyzed anti-stereocontrolled ring-opening of oxabicyclic alkenes with various Grignard reagents was reported, which afforded the corresponding anti-2-substituted-1,2-dihydronaphthalen-1-ol products with moderate to good yields in the presence of a catalytic amount of Pt(PPh 3)4 (2.5 mol%) under mild conditions. The effects of catalyst loading, solvent and temperature on the yield were also investigated. Furthermore, the trans-configuration of the product 5i was confirmed by X-ray diffraction analysis.