5043-00-5 Usage
Uses
Used in Pharmaceutical Industry:
6-FLUORO-2-NAPHTHOIC ACID METHYL ESTER is used as a key intermediate in the synthesis of various pharmaceuticals for its potential biological activities. It contributes to the development of new drugs by providing a structural foundation that can be further modified to achieve desired therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical sector, 6-FLUORO-2-NAPHTHOIC ACID METHYL ESTER is employed as a precursor in the production of agrochemicals. Its unique chemical properties allow for the creation of compounds with specific pesticidal or herbicidal activities, enhancing crop protection and yield.
Used in Organic Synthesis:
6-FLUORO-2-NAPHTHOIC ACID METHYL ESTER is utilized as a reagent in organic synthesis, facilitating the formation of complex organic molecules. Its presence can influence the reactivity and selectivity of reactions, enabling the synthesis of a wide range of organic compounds.
Used in Production of Fluorine-Containing Compounds:
As a starting material, 6-FLUORO-2-NAPHTHOIC ACID METHYL ESTER is essential in the production of other fluorine-containing compounds. The introduction of fluorine atoms into organic molecules can significantly alter their properties, making 6-FLUORO-2-NAPHTHOIC ACID METHYL ESTER a valuable resource in the synthesis of fluorinated materials with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 5043-00-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,0,4 and 3 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5043-00:
(6*5)+(5*0)+(4*4)+(3*3)+(2*0)+(1*0)=55
55 % 10 = 5
So 5043-00-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H9FO2/c1-15-12(14)10-3-2-9-7-11(13)5-4-8(9)6-10/h2-7H,1H3
5043-00-5Relevant academic research and scientific papers
Catalytic Ester to Stannane Functional Group Interconversion via Decarbonylative Cross-Coupling of Methyl Esters
Yue, Huifeng,Zhu, Chen,Rueping, Magnus
, p. 385 - 388 (2018/01/27)
An unprecedented conversion of methyl esters to stannanes was realized, providing access to a series of arylstannanes via nickel catalysis. Various common esters including ethyl, cyclohexyl, benzyl, and phenyl esters can undergo the newly developed decarbonylative stannylation reaction. The reaction shows broad substrate scope, can differentiate between different types of esters, and if applied in consecutive fashion, allows the transformation of methyl esters into aryl fluorides or biaryls via fluororination or arylation.
De Novo Synthesis of Phenols and Naphthols through Oxidative Cycloaromatization of Dienynes
Rong, Ming-Guang,Qin, Tian-Zhu,Liu, Xin-Rui,Wang, Hong-Fa,Zi, Weiwei
supporting information, p. 6289 - 6293 (2018/10/09)
In this work, a rhodium-catalyzed oxidative cycloaromatization of dienynes, which provides a highly straightforward and efficient way to access polysubstituted naphthols and phenols under mild conditions, is described. Challenged electron-withdrawing groups are well tolerated in this protocol, and late-stage phenyl ring formation is demonstrated.
Palladium-Catalyzed Alkynylation of Morita-Baylis-Hillman Carbonates with (Triisopropylsilyl)acetylene on Water
Li, Yangxiong,Liu, Li,Kong, Delong,Wang, Dong,Feng, Weichun,Yue, Tao,Li, Chaojun
, p. 6283 - 6290 (2015/06/30)
Direct alkynylation of Morita-Baylis-Hillman carbonates with (triisopropylsilyl)acetylene catalyzed by a Pd(OAc)2-NHC complex was developed "on water" to give the corresponding 1,4-enynes. The significant effects of water amount in the solvent
