50554-93-3

Upstream product

• 130422-33-2 N-(Ethoxycarbonylmethyl)-4-(phenylthio)butanamide 
• 17742-51-7 4-phenylsulfanyl-butyric acid 
• 108-98-5 thiophenol 
• 55582-10-0 2-<4-(Phenylthio)butyl>-1H-isoindole-1,3(2H)-dione 
• 17742-54-0 4-phenylsulfanyl-1-bromobutane 

Downstream Products

• 1414792-75-8 (4-isothiocyanatobutyl)(phenyl)sulfane 
• 1356472-64-4 ((4-isothiocyanatobutyl)sulfinyl)benzene 
• 156996-50-8 (N-{4-phenylthio-n-butyl})aminomethanediphosphonic acid tetraethyl ester 
• 116414-35-8 N-<4-(Phenylsulfinyl)butyl>acetamide 
• 116414-41-6 N-Acetyl-2-(phenylthio)pyrrolidine 

Relevant academic research and scientific papers

Synthesis of (+)-Lentiginosine and Its Pyrrolizidine Analogue Based on Intramolecular Cyclization of α-Sulfinyl Carbanions

A synthesis of (+)-lentiginosine and its pyrrolizidine analogue was accomplished in six steps, starting from L-(+)-tartaric acid. The key step of these syntheses involves the intramolecular cyclization of α-sulfinyl carbanions for the construction of the indolizidine or pyrrolizidine ring.

Synthesis and biological evaluation of sulforaphane derivatives as potential antitumor agents

A series of sulforaphane derivatives were synthesized and evaluated in vitro for their cytotoxicity against five cancer cell lines (HepG2, A549, MCF-7, HCT-116 and SH-SY5Y). The pharmacological results showed that many of the derivatives displayed more potent cytotoxicity than sulforaphane (SFN). Furthermore, SFN and derivative 85 could induce cell cycle arrest at S or G2/M phase and cell apoptosis. SFN and 85 exhibited time- and dose-dependent activation on Nrf2 transcription factor, and 85 acted as a more potent Nrf2 inducer than SFN.