5068-21-3

Usage

Uses

Used in Coordination Chemistry:
(4-HYDROXYPHENYL)DIPHENYLPHOSPHINE is used as a phosphine ligand for enhancing the stability and reactivity of metal complexes. Its unique structure allows for the fine-tuning of the electronic and steric properties of the complexes, which is crucial for optimizing their performance in various chemical reactions.
Used in Organometallic Chemistry:
In organometallic chemistry, (4-HYDROXYPHENYL)DIPHENYLPHOSPHINE is used as a ligand to form organometallic complexes. These complexes are essential in catalytic reactions and can be employed in the synthesis of various organic compounds, contributing to the advancement of synthetic chemistry.
Used in Catalytic Reactions:
(4-HYDROXYPHENYL)DIPHENYLPHOSPHINE is used as a ligand in catalytic reactions to improve the efficiency and selectivity of the process. Its presence in the catalyst system can lead to better control over the reaction pathways, resulting in higher yields and more environmentally friendly processes.
Used in the Synthesis of Organometallic Complexes:
(4-HYDROXYPHENYL)DIPHENYLPHOSPHINE is used as a key component in the synthesis of various organometallic complexes, which have applications in areas such as homogeneous catalysis, materials science, and pharmaceuticals. The organometallic complexes synthesized using (4-HYDROXYPHENYL)DIPHENYLPHOSPHINE can exhibit unique properties and reactivities due to the presence of this versatile ligand.

InChI:InChI=1/C18H15OP/c19-15-11-13-18(14-12-15)20(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14,19H

Upstream product

• 540-38-5 p-Iodophenol 
• 829-85-6 diphenylphosphane 
• 795-44-8 4-(diphenylphosphoryl)benzonitrile 
• 1499-21-4 Diphenylphosphinic chloride 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 793-43-1 (4-Hydroxyphenyl)diphenylphosphine oxide 
• 67963-68-2 t-butyldimethylsilyl-4-bromophenol 
• 1079-66-9 chloro-diphenylphosphine 
• 937378-85-3 [(η⁶-p-cymene)RuCl₂(κP-PPh₂(4-C₆H₄OH))] 
• 896-89-9 (4-methoxyphenyl)diphenylphosphane 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 106-41-2 4-bromo-phenol 
• 528609-62-3 (4-hydroxyphenyl)diphenylphosphine borane 
• 238403-27-5 4-(tert-butyldimethylsiloxy)phenyldiphenylphosphine 

Downstream Products

• 793-43-1 (4-Hydroxyphenyl)diphenylphosphine oxide 
• 20650-56-0 p-hydroxyphenyl(diphenyl)phosphine sulfide 
• 394657-29-5 p-hydroxyphenyl(diphenyl)phosphine selenide 
• 507225-10-7 Mn(CO)2(η5-C5H4CH3)(P(C6H5)2(C6H4OH) 
• 702702-33-8 HOC₆H₄P(C₆H₅)2*Fe⁽²⁺⁾*C₅H₅^(1-)*(CH₂P(C₆H₅)2)2*PF₆^(1-)=[HOC₆H₄P(C₆H₅)2Fe(C₅H₅)((CH₂P(C₆H₅)2)2)]PF₆ 
• 937378-85-3 [(η⁶-p-cymene)RuCl₂(κP-PPh₂(4-C₆H₄OH))] 
• 1353567-03-9 1-(4-diphenylphosphinophenolato)-2,8,9-trioxa-5-aza-3,3,7,7,10,10-hexamethylstannatricyclo[3.3.3.0(1.5)]undecane 
• 528609-62-3 (4-hydroxyphenyl)diphenylphosphine borane 

Relevant academic research and scientific papers

Ultrashort Hδ+?Hδ?intermolecular distance in a supramolecular system in the solid state

Herein we report experimental evidence for the shortest intermolecular distance reported for two electronically-different hydrogen atoms in the solid state. The Hδ+?Hδ?non-covalent interaction was studied using theoretical calculatio

Phosphite sodium salt modified amphipathic phosphorus-containing crown macromolecule nano micelle and preparation and application thereof

The invention relates to a phosphite sodium salt modified amphipathic phosphorus-containing crown macromolecule nano micelle and a preparation method and application thereof. The preparation method is simple, the controllability of the reaction process is high, and the operation is easy. Compared with the reported polyamide - amine type crown macromolecule nano-micelle, the nano material has higher encapsulation efficiency, loading rate and better anti-inflammatory effect, can effectively improve the treatment effect of the hydrophobic drug, and has good application prospects.

Phosphine boranes as less hydrophobic building blocks than alkanes and silanes: Structure-property relationship and estrogen-receptor-modulating potency of 4-phosphinophenol derivatives

Increasing structural options in medicinal chemistry is important for the development of novel and distinctive drug candidates. In this study, we focused on phosphorus-containing functionalities. We designed and synthesized a series of phosphinophenol der

Shuttling Catalyst: Facilitating C?C Bond Formation via Cross-Couplings with a Thermoresponsive Polymeric Ligand

A poly(ethylene glycol) (PEG) linked ortho-MeO-phenyldicyclohexylphosphine (MeO-WePhos) ligand has been synthesized to promote Pd-catalyzed carbon-carbon bond formation by cross-couplings including Sonogashira, Heck, Hiyama and Stille reactions, providing corresponding (hetero)aryl substituted alkynes, alkenes and bi(hetero)aryls in good to excellent isolated yields with low Pd loadings. Facilitated by the lower critical solution temperature behaviour of the polymeric monophosphine ligand, the metal-complex could rapidly shuttle between organic and water phases as regulated by temperature, enabling highly efficient catalyst recycling via a simple phase separation. The chemical structure of ligand was determined by matrix-assisted laser desorption/ionization-time of flight mass spectrometry, nuclear magnetic resonance spectrometry and size-exclusion chromatography measurements. Notably, as demonstrated by the inductively coupled plasma-atomic emission spectrometry measurement, 98% Pd was kept in the water phase after 6 cycles of catalyst recycling experiments. Given the profound impact of transition-metal-catalyzed covalent bond formation and the increasing demand of sustainable chemistry, this work provides an alternative method to conduct cross-couplings with a polymeric shuttling catalyst.

Preparation method of amphiphilic PN = PS type phosphorus-containing crown macromolecular nano-micelle and application of crown macromolecular nano-micelle as drug carrier

The invention relates to a preparation method of amphipathic PN = PS type phosphorus-containing crown macromolecule nano-micelle and application of the crown macromolecular nano-micelle as a drug carrier. The obtained amphipathic phosphorus-containing crown macromolecule can be self-assembled into the nano-micelle in water, and a hydrophobic drug can be embedded into a hydrophobic cavity in the nano-micelle to form a stable compound. The method disclosed by the invention is simple, high in reaction controllability, easy in operation and separation, low in cost, uniform in final product molecular weight and commercialized in raw material source, and has a good development prospect.

Readily Available Immobilized Pd Catalysts for Suzuki-Miyaura Coupling under Continuous-flow Conditions

Highly efficient immobilized catalysts for continuous-flow cross-coupling reactions that show better productivity than those for the corresponding batch reactions are increasingly in demand. For practical use, such catalysts should have highly catalytic activity and high leaching resistance. To find catalysts suitable for continuous-flow conditions, we have developed a consistent method for evaluating the catalytic performance of commercially available immobilized Pd catalysts. Monitoring of the change in turnover frequency over time under excess substrate loading conditions revealed the limitation of these catalysts. On the basis of the evaluation results, we have successfully developed a new immobilized Pd catalyst that exhibited highly efficient and robust catalytic performance.

PHOSPHONIUM COMPOUND AND PRODUCTION METHOD THEREFOR

The present invention provides a phosphonium compound of formula (II). Also provided is a method for producing a quaternary phosphonium compound labeled with a positron emitting radionuclide, the method comprising the step of reacting an electrophile of f

A general strategy to add diversity to ruthenium arene complexes with bioactive organic compounds: Via a coordinated (4-hydroxyphenyl)diphenylphosphine ligand

Esterification of (4-hydroxyphenyl)diphenylphosphine, coordinated to the [Ru(η6-p-cymene)Cl2] fragment, allows a series of bioactive carboxylic acids to be introduced directly into the organometallic molecule. Evaluation of the compounds on human ovarian cancer cells reveals synergistic enhancements in their antiproliferative activity relative to their bioactive organic and organometallic precursors.

Early-Late Heterometallic Complexes of Gold and Zirconium: Photoluminescence and Reactivity

OH functionalized triarylphosphines were used to assemble zirconocene-based metalloligands with phosphine donor sites in varying positions. These complexes were subsequently treated with different gold precursors to obtain early-late heterometallic compou

PHOSPHONIUM COMPOUND OR INTERMOLECULAR SALT THEREOF, AND METHOD OF PRODUCING THE SAME

PROBLEM TO BE SOLVED: To provide a compound useful as a curing accelerator of an epoxy resin composition and a method of producing the same. SOLUTION: This invention provides a phosphonium compound represented by general formula (I-1) or intermolecular sa