50793-44-7

Upstream product

• 10325-67-4 2,3-dibromo-3-(4-methoxy-phenyl)-1-phenyl-propan-1-one 
• 90399-67-0 2-bromo-3-methoxy-3-(4-methoxy-phenyl)-1-phenyl-propan-1-one 
• 50999-22-9 3-ethoxy-2-bromo-3-(4-methoxy-phenyl)-1-phenyl-propan-1-one 
• 123-11-5 4-methoxy-benzaldehyde 
• 98-86-2 acetophenone 
• 22252-15-9 trans-4-methoxychalcone 
• 959-33-1 3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one 
• 64-17-5 ethanol 

Downstream Products

• 135549-16-5 8-(4-Methoxy-phenyl)-6-phenyl-3-p-tolyloxymethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine 
• 135549-18-7 8-(4-Methoxy-phenyl)-6-phenyl-3-o-tolyloxymethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine 
• 135549-11-0 8-(4-Methoxy-phenyl)-6-phenyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine 
• 135549-12-1 8-(4-Methoxy-phenyl)-3-methyl-6-phenyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine 
• 135549-13-2 3-Ethyl-8-(4-methoxy-phenyl)-6-phenyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine 
• 135549-14-3 8-(4-Methoxy-phenyl)-6-phenyl-3-propyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine 
• 135549-15-4 8-(4-Methoxy-phenyl)-3,6-diphenyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine 
• 135549-17-6 3-(4-Chloro-phenoxymethyl)-8-(4-methoxy-phenyl)-6-phenyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine 
• 135549-19-8 3-(2-Chloro-phenoxymethyl)-8-(4-methoxy-phenyl)-6-phenyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine 
• 3672-51-3 5-(4-methoxyphenyl)-3-phenylisoxazole 
• 1221289-08-2 C₂₄H₁₈O₂ 
• 65-85-0 benzoic acid 

Relevant academic research and scientific papers

Modular access to 1,2-allenyl ketones based on a photoredox-catalysed radical-polar crossover process

Herein, a new protocol dealing with the preparation of 1,2-allenyl ketones has been successfully developedviathe reactions of enynes with radicals enabled by dual photoredox/copper catalysis. Based on the results of a deuteration experiment and the competition reaction between cyclopropanation and allenation, the mechanism based on a photoredox-neutral-catalysed radical-polar crossover process has been proposed. Synthetic applications of allenes have also been demonstrated.

Visible light-mediated metal-free double bond deuteration of substituted phenylalkenes

Various bromophenylalkenes were reductively photodebrominated by using 1,3-dimethyl-2-phenyl-1H-benzo-[d]imidazoline (DMBI) and 9,10-dicyanoanthracene. With deuterated DMBI analogs (the most effective was DMBI-d11), satisfactory to excellent isotopic yields were obtained. DMBI-d11 could also be regenerated from the reaction mixtures with a recovery rate of up to 50%. The combination of the photodebromination reaction with conventional methods for bromoalkene synthesis enables sequential monodeuteration of a double bond without the necessity of a metal catalyst. This journal is

Sc(OTf)3-Catalyzed Diastereoselective Formal [3+2] Cycloaddition Reactions of Alkynylcyclopropane Ketones with Electron-Rich Aromatic Aldehydes to Yield 2,5-trans-Tetrahydrofurans

In contast to the general [4+2] cycloaddition reactions of alkynylcyclopropane ketones reported in the literature, we report herein a Sc(OTf)3-catalyzed formal intermolecular [3+2] cycloaddition reaction of alkynylcyclopropane ketones with elec

Chemoselective C-C bond cleavage of epoxide motifs: Gold(I)-catalyzed diastereoselective [4+3] cycloadditions of 1-(1-Alkynyl)oxiranyl ketones and nitrones

Cutting carbon! A novel facile strategy for the C-C bond cleavage of oxiranyl ketones has been developed. Carbophilic gold(I) activation of the alkyne side chain mediates a heterocyclization and subsequent C-C bond cleavage (see scheme).

New Derivatives of N-Vinyltriazoles: 1,3-Diaryl-3-(1H-1,2,4-triazol-1-yl)-2-propen-1-ones

We have synthesized previously unknown N-vinyltriazoles: 1,3-diaryl-3-(1H-1,2,4-triazol-1-yl)-2-propen-1-ones.We discusss a hypothesis for a probable reaction mechanism.

Reaction of 4-amino-5-mercapto-1,2,4-triazoles with chalcone dibromides and α-bromochalcones

Four α-bromochalcones (2) have been condensed with some 3-substituted-4-amino-5-mercapto-1,2,4-triazoles (3) in the presence of ethanolic KOH to yield hitherto unreported 6,8-diaryl-1,2,4-triazolothiadiazepines (4), whose structure has been established on the basis of analytical and spectral data.The chalcone dibromide (1) when treated with 4-amino-5-mercapto-1,2,4-triazoles (3) in the presence of triethylamine undergoes debromination to give the corresponding chalcones.

E1cB Elimination from 2-Halogeno-3-methoxy-1,3-diphenylpropan-2-ones

Kinetic and stereochemical evidence has been obtained from the dehydromethoxylation of 2-halogeno-3-methoxy-1,3-diphenylpropan-2-ones with isopropoxide in isopropyl alcohol that is consistent with an E1cB reversible mechanism.The influence of the halogen both on the deprotonation rate and upon the methoxy-group expulsion has been evaluated.