50920-64-4

Usage

Uses

Used in Pharmaceutical Industry:
4-BROMO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER is used as an intermediate in the synthesis of various pharmaceuticals for its potential therapeutic applications. Its ability to inhibit certain enzymes makes it a promising candidate for the development of drugs targeting specific diseases.
Used in Agrochemical Industry:
In the agrochemical sector, 4-BROMO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER serves as an intermediate in the production of agrochemicals. Its enzyme-inhibiting properties can be harnessed to create compounds that address pest control and crop protection needs.
Used in Research and Development:
4-BROMO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER is utilized in research and development settings to explore its potential in treating various diseases, particularly cancer. Its inhibitory effects on enzymes are of interest to scientists working on novel therapeutic approaches.
Used as a Specialty Chemical:
Due to its unique properties, 4-BROMO-1,3-DIMETHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER is also used as a specialty chemical in various industrial applications where its specific characteristics are required for the development of new products or processes.

Upstream product

• 74-96-4 ethyl bromide 
• 4027-57-0 ethyl 5-methyl-2H-pyrazole-3-carboxylate 
• 624-80-6 ethylhydrazine 
• 615-79-2 ethyl 2,4-diketopentanoate 
• 75-00-3 chloroethane 
• 64-67-5 diethyl sulfate 
• 95-92-1 oxalic acid diethyl ester 
• 67-64-1 acetone 
• 50920-65-5 1-ethyl-3-methyl-1H-pyrazole-5-carboxylic acid 
• 64-17-5 ethanol 

Downstream Products

• 94192-28-6 N-[4-(2-Ethyl-5-methyl-2H-pyrazole-3-carbonyl)-2,5-dimethyl-2H-pyrazol-3-yl]-benzamide 
• 50920-65-5 1-ethyl-3-methyl-1H-pyrazole-5-carboxylic acid 
• 128537-47-3 1-ethyl-3-methyl-4-chloro-5-pyrazolecarboxylic acid ethyl ester 
• 1253430-02-2 3-(1-ethyl-3,4-dimethylpyrazol-5-yl)-2-(4-tertbutylphenyl)-3-hydroxyl-acrylonitrile 
• 1253431-45-6 3-(4-chloro-1-ethyl-3-methylpyrazol-5-yl)-2-(4-tertbutylphenyl)-3-hydroxy-acrylonitrile 

Relevant academic research and scientific papers

A method for preparing acetazole nitrile intermediate

The present invention relates to chemical synthesis, in particular a method for preparing a thyazole mite nitrile intermediate (3-methyl-1-ethyl-1H- ethylazole-5-carboxylate) method. The pyrazole ester under solvent conditions, added an acid binding agent and catalyst, into the system into the halogenated ethane gas, the reaction to qualified, to obtain ethyl. The present invention uses haloethane instead of diethyl sulfate for ethylation reaction, the reaction raw material is cheap and easy to obtain, and the process of post-treatment with water is cancelled, the COD emission is reduced directly from the process source, and the reaction cycle is greatly reduced.

Modulators of STING (Stimulator of Interferon Genes)

Compounds of the general formula (I): or a pharmaceutically acceptable salt thereof, processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.

STING AGONISTS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the modulation of STING, and the treatment of STING-mediated disorders.

PYRAZOLE DERIVATIVE

A pyrazole derivative having the following formula stru-1: The pyrazole derivative is used for prevention and control of pests.

Method for preparing 1-alkyl-3-alkylpyrazole-5-carboxylate

The invention discloses a preparation method of a compound shown in a formula (I). The compound is prepared through three-step reactions comprising condensation, condensation cyclization and alkylation, The preparation method provided by the invention can realize one-pot operation, a reactor is not required to be replaced, the yield of the prepared product is high, and the method is suitable for industrial production.

METHODS FOR ADMINISTERING STING AGONISTS

The present invention relates to methods of treating disease states, including cancer, in a human comprising systemically administering a STING agonist, or a pharmaceutically acceptable salt thereof, to said human.

MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) USEFUL IN TREATING HIV

Disclosed are compounds having the formula: (I-N) wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, and R17, are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof, along with combinations thereof, all of which are useful in HIV therapies.

Phenyl ether oxadiazole insecticide

The invention provides a phenyl ether oxadiazole insecticide having a chemical structure as shown in Formula I described in the description. The compound of the formula I has excellent insecticidal activity and can be used to control agricultural or forestry pests.

A class of pyrazole derivatives, preparation method and application thereof (by machine translation)

The invention discloses a following formula stru - 1 indicated by the pyrazole derivatives, The definition of each substituent in the specification. This invention relates to pyrazole derivatives suitable for use in the pest. (by machine translation)

HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS

Disclosed are compounds having the formula (I-N), wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, and R17, are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.