5100-36-7 Usage
Uses
Used in Pharmaceutical Synthesis:
ETHYL 6-ISOCYANATOHEXANOATE is used as an intermediate in the synthesis of 1-(5-ethoxycarbonylpentylcarbamoyl)-5-fluorouracil, a compound with potential pharmaceutical applications. Its role in this synthesis is crucial for the development of new drugs and therapies in the medical field.
Check Digit Verification of cas no
The CAS Registry Mumber 5100-36-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,0 and 0 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5100-36:
(6*5)+(5*1)+(4*0)+(3*0)+(2*3)+(1*6)=47
47 % 10 = 7
So 5100-36-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H15NO3/c1-2-13-9(12)6-4-3-5-7-10-8-11/h2-7H2,1H3
5100-36-7Relevant academic research and scientific papers
Potential anticancer agents: 5-(N-substituted-aminocarbonyl)- and 5-(N-substituted-aminothiocarbonyl)-5,6,7,8-tetrahydrofolic acids
Temple Jr.,Elliott,Montgomery
, p. 697 - 700 (2007/10/02)
5-[[N-[(Ethoxycarbonyl)alkyl]amino]carbonyl] (6-9) and the corresponding aminothiocarbonyl (12-15) derivatives of 5,6,7,8-tetrahydrofolic acid were prepared as multisubstrate analogues of the substrate-cofactor adduct in the reactions catalyzed by the folate-mediated one-carbon transfer reactions. Evaluation in vitro showed that 7 (alkyl = hexyl) was cytotoxic to H.Ep-2 cells (ED50, 4 μM) but noncytotoxic to proliferating L1210 cells. No activity was observed for 7 against the P388 leukemia in mice.
